Clinical results of an HBV-specific T-cell receptor-T-cell therapy (SCG101) in patients with HBV-related hepatocellular carcinoma treated in an investigator-initiated, interventional trial.

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Title: Clinical results of an HBV-specific T-cell receptor-T-cell therapy (SCG101) in patients with HBV-related hepatocellular carcinoma treated in an investigator-initiated, interventional trial.
Authors: Wu X; Department of Liver Surgery, Peking Union Medical College Hospital, Beijing, Beijing, China., Quan D; Department of General Surgery, The Sixth People's Hospital of Shenyang, Shenyang, China., Li W; Department of Medical Oncology, Zhongshan Hospital Fudan University, Shanghai, Shanghai, China., Wisskirchen K; SCG Cell Therapy GmbH, Munich, Germany., Wu W; Department of General Surgery, The Sixth People's Hospital of Shenyang, Shenyang, China., Zhou Y; Department of Medical Oncology, Zhongshan Hospital Fudan University, Shanghai, Shanghai, China., Liu YP; Department of Medical Oncology, The First Hospital of China Medical University, Shenyang, China., Wan X; Department of Liver Surgery, Peking Union Medical College Hospital, Beijing, Beijing, China., Wang X; SCG Cell Therapy Pte Ltd, Singapore., Zhang X; SCG (Shanghai) Cell Therapy Co Ltd, Shanghai, China., Yang L; SCG (Shanghai) Cell Therapy Co Ltd, Shanghai, China., Zheng M; SCG (Shanghai) Cell Therapy Co Ltd, Shanghai, China., Zhang K; SCG Cell Therapy Pte Ltd, Singapore., Protzer U; Institute of Virology, Technical University of Munich / Helmholtz Munich, Munich, Germany protzer@tum.de dushd@pumch.cn qu_xiujuan@hotmail.com.; German Center for Infection Research, Munich, Germany., Du S; Department of Liver Surgery, Peking Union Medical College Hospital, Beijing, Beijing, China protzer@tum.de dushd@pumch.cn qu_xiujuan@hotmail.com., Qu X; Department of Medical Oncology, The First Hospital of China Medical University, Shenyang, China protzer@tum.de dushd@pumch.cn qu_xiujuan@hotmail.com.
Source: Gut [Gut] 2025 Dec 05; Vol. 75 (1), pp. 147-160. Date of Electronic Publication: 2025 Dec 05.
Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1468-3288
DOI:10.1136/gutjnl-2025-335456