View in EDS HTML Full Text PDF Full Text

PAM-interacting domain turn-helix 51 motifs can improve Cas9-SpRY activity.

Saved in:
Bibliographic Details
Title: PAM-interacting domain turn-helix 51 motifs can improve Cas9-SpRY activity.
Authors: Eggenschwiler R; Research Group Translational Hepatology and Stem Cell Biology, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.; REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, 30625 Hannover, Germany., Hoffmann T; Molecular Systems Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany., Dmytrenko O; Helmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, 97080 Würzburg, Germany., Opitz M; Research Group Translational Hepatology and Stem Cell Biology, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.; REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, 30625 Hannover, Germany., Ackel-Zakour M; Research Group Translational Hepatology and Stem Cell Biology, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.; REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, 30625 Hannover, Germany., Wang P; Research Group Translational Hepatology and Stem Cell Biology, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.; REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, 30625 Hannover, Germany., McCallan SA; Research Group Translational Hepatology and Stem Cell Biology, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.; REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, 30625 Hannover, Germany., Fráguas-Eggenschwiler M; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany., Niemann H; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany., Patronov A; Discovery Sciences, R&D, AstraZeneca Gothenburg, 43183 Mölndal, Sweden., Beisel CL; Helmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, 97080 Würzburg, Germany.; Medical Faculty, University of Würzburg, 97080 Würzburg, Germany., Cantz T; Research Group Translational Hepatology and Stem Cell Biology, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.; REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, 30625 Hannover, Germany.
Source: Nucleic acids research [Nucleic Acids Res] 2025 Aug 11; Vol. 53 (15).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40808297
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: PAM-interacting domain turn-helix 51 motifs can improve Cas9-SpRY activity.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Eggenschwiler+R%22">Eggenschwiler R</searchLink>; Research Group Translational Hepatology and Stem Cell Biology, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.; REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, 30625 Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Hoffmann+T%22">Hoffmann T</searchLink>; Molecular Systems Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Dmytrenko+O%22">Dmytrenko O</searchLink>; Helmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Opitz+M%22">Opitz M</searchLink>; Research Group Translational Hepatology and Stem Cell Biology, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.; REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, 30625 Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Ackel-Zakour+M%22">Ackel-Zakour M</searchLink>; Research Group Translational Hepatology and Stem Cell Biology, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.; REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, 30625 Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Wang+P%22">Wang P</searchLink>; Research Group Translational Hepatology and Stem Cell Biology, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.; REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, 30625 Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22McCallan+SA%22">McCallan SA</searchLink>; Research Group Translational Hepatology and Stem Cell Biology, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.; REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, 30625 Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Fráguas-Eggenschwiler+M%22">Fráguas-Eggenschwiler M</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Niemann+H%22">Niemann H</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Patronov+A%22">Patronov A</searchLink>; Discovery Sciences, R&D, AstraZeneca Gothenburg, 43183 Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Beisel+CL%22">Beisel CL</searchLink>; Helmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, 97080 Würzburg, Germany.; Medical Faculty, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Cantz+T%22">Cantz T</searchLink>; Research Group Translational Hepatology and Stem Cell Biology, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.; REBIRTH-Research Center for Translational Regenerative Medicine, Hannover Medical School, 30625 Hannover, Germany.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220411011%22">Nucleic acids research</searchLink> [Nucleic Acids Res] 2025 Aug 11; Vol. 53 (15).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0411011 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1362-4962 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203051048%22">03051048 </searchLink><i>NLM ISO Abbreviation: </i>Nucleic Acids Res <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40808297
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1093/nar/gkaf782
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: PAM-interacting domain turn-helix 51 motifs can improve Cas9-SpRY activity.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Eggenschwiler R
      – PersonEntity:
          Name:
            NameFull: Hoffmann T
      – PersonEntity:
          Name:
            NameFull: Dmytrenko O
      – PersonEntity:
          Name:
            NameFull: Opitz M
      – PersonEntity:
          Name:
            NameFull: Ackel-Zakour M
      – PersonEntity:
          Name:
            NameFull: Wang P
      – PersonEntity:
          Name:
            NameFull: McCallan SA
      – PersonEntity:
          Name:
            NameFull: Fráguas-Eggenschwiler M
      – PersonEntity:
          Name:
            NameFull: Niemann H
      – PersonEntity:
          Name:
            NameFull: Patronov A
      – PersonEntity:
          Name:
            NameFull: Beisel CL
      – PersonEntity:
          Name:
            NameFull: Cantz T
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 11
              M: 08
              Text: 2025 Aug 11
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1362-4962
          Numbering:
            – Type: volume
              Value: 53
            – Type: issue
              Value: 15
          Titles:
            – TitleFull: Nucleic acids research
              Type: main
ResultId 1