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Unraveling the genetic link: causal effects and PRS predictions of adiposity-related health conditions in East Asian individuals.

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Title: Unraveling the genetic link: causal effects and PRS predictions of adiposity-related health conditions in East Asian individuals.
Authors: Lin YJ; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan., Li JP; Department of Pathology, School of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan., Liu TY; Million-person Precision Medicine Initiative, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan., Chiou JS; PhD Program for Health Science and Industry, College of Health Care, China Medical University, Taichung, Taiwan.; Department of Health Services Administration, China Medical University, Taichung, Taiwan., Lu HF; Million-person Precision Medicine Initiative, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Ariyoshi K; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Division of Medical Biophysics, Department of Biophysics, Graduate School of Health Sciences, Kobe University, Kobe, Japan., Uchiyama S; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Terao C; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan.; Department of Applied Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan., Yang JS; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan., Chou CH; PhD Program for Health Science and Industry, College of Health Care, China Medical University, Taichung, Taiwan.; Department of Health Services Administration, China Medical University, Taichung, Taiwan., Liang WM; Department of Health Services Administration, China Medical University, Taichung, Taiwan., Chou IC; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan.; Department of Pediatric Neurology, China Medical University Children's Hospital, Taichung, Taiwan.; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan., Lin CW; PhD Program for Health Science and Industry, College of Health Care, China Medical University, Taichung, Taiwan.; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan., Lin TH; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan., Liao CC; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan., Huang SM; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan., Tsai FJ; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan.; Division of Medical Genetics, China Medical University Children's Hospital, Taichung, Taiwan.; Department of Medical Laboratory Science & Biotechnology, Asia University, Taichung, Taiwan.
Source: Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2025 Sep; Vol. 33 (9), pp. 1765-1778. Date of Electronic Publication: 2025 Aug 14.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101264860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1930-739X (Electronic) Linking ISSN: 19307381 NLM ISO Abbreviation: Obesity (Silver Spring) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Unraveling the genetic link: causal effects and PRS predictions of adiposity-related health conditions in East Asian individuals.
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  Data: <searchLink fieldCode="AU" term="%22Lin+YJ%22">Lin YJ</searchLink>; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Li+JP%22">Li JP</searchLink>; Department of Pathology, School of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+TY%22">Liu TY</searchLink>; Million-person Precision Medicine Initiative, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiou+JS%22">Chiou JS</searchLink>; PhD Program for Health Science and Industry, College of Health Care, China Medical University, Taichung, Taiwan.; Department of Health Services Administration, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lu+HF%22">Lu HF</searchLink>; Million-person Precision Medicine Initiative, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Ariyoshi+K%22">Ariyoshi K</searchLink>; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Division of Medical Biophysics, Department of Biophysics, Graduate School of Health Sciences, Kobe University, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Uchiyama+S%22">Uchiyama S</searchLink>; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Terao+C%22">Terao C</searchLink>; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan.; Department of Applied Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Yang+JS%22">Yang JS</searchLink>; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chou+CH%22">Chou CH</searchLink>; PhD Program for Health Science and Industry, College of Health Care, China Medical University, Taichung, Taiwan.; Department of Health Services Administration, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liang+WM%22">Liang WM</searchLink>; Department of Health Services Administration, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chou+IC%22">Chou IC</searchLink>; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan.; Department of Pediatric Neurology, China Medical University Children's Hospital, Taichung, Taiwan.; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CW%22">Lin CW</searchLink>; PhD Program for Health Science and Industry, College of Health Care, China Medical University, Taichung, Taiwan.; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+TH%22">Lin TH</searchLink>; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liao+CC%22">Liao CC</searchLink>; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+SM%22">Huang SM</searchLink>; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+FJ%22">Tsai FJ</searchLink>; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan.; Division of Medical Genetics, China Medical University Children's Hospital, Taichung, Taiwan.; Department of Medical Laboratory Science & Biotechnology, Asia University, Taichung, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101264860%22">Obesity (Silver Spring, Md.)</searchLink> [Obesity (Silver Spring)] 2025 Sep; Vol. 33 (9), pp. 1765-1778. <i>Date of Electronic Publication: </i>2025 Aug 14.
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        Value: 10.1002/oby.24335
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        Text: English
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