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Engineered human B cells targeting tumor-associated antigens exhibit antigen presentation and antibody-mediated functions.

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Title: Engineered human B cells targeting tumor-associated antigens exhibit antigen presentation and antibody-mediated functions.
Authors: Boucher A; ElevateBio, Waltham, MA, United States., Anderson C; Tabby Therapeutics, Watertown, MA, United States., Hinman R; Tabby Therapeutics, Watertown, MA, United States., Kindschuh M; Tabby Therapeutics, Watertown, MA, United States., Fung J; Tabby Therapeutics, Watertown, MA, United States., Wang T; ElevateBio, Waltham, MA, United States., Klooster I; ElevateBio, Waltham, MA, United States., Kim E; ElevateBio, Waltham, MA, United States., Roth C; Life Edit Therapeutics, Durham, NC, United States., Vander Oever M; Life Edit Therapeutics, Durham, NC, United States., Khan B; ElevateBio, Waltham, MA, United States., Zelikson N; Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel., Vagima Y; Department of Biotechnology, Israel Institute for Biological Research, Ness Ziona, Israel., Saribasak H; ElevateBio, Waltham, MA, United States., Santry L; ElevateBio, Waltham, MA, United States., Klapper LN; Tabby Therapeutics, Ness Ziona, Israel., Hess S; Tabby Therapeutics, Ness Ziona, Israel., Mooney J; ElevateBio, Waltham, MA, United States., Bublik DR; Tabby Therapeutics, Ness Ziona, Israel., Laken H; Tabby Therapeutics, Watertown, MA, United States., Barzel A; Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel., Borden P; Life Edit Therapeutics, Durham, NC, United States., Plewa C; ElevateBio, Waltham, MA, United States., Chadbourne AM; ElevateBio, Waltham, MA, United States., Bridgen D; Tabby Therapeutics, Watertown, MA, United States., Nahmad AD; Tabby Therapeutics, Ness Ziona, Israel.; The Samueli Integrative Cancer Pioneering Institute, Petah Tikva, Israel.
Source: Frontiers in immunology [Front Immunol] 2025 Jul 30; Vol. 16, pp. 1621222. Date of Electronic Publication: 2025 Jul 30 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Engineered human B cells targeting tumor-associated antigens exhibit antigen presentation and antibody-mediated functions.
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  Data: <searchLink fieldCode="AU" term="%22Boucher+A%22">Boucher A</searchLink>; ElevateBio, Waltham, MA, United States.<br /><searchLink fieldCode="AU" term="%22Anderson+C%22">Anderson C</searchLink>; Tabby Therapeutics, Watertown, MA, United States.<br /><searchLink fieldCode="AU" term="%22Hinman+R%22">Hinman R</searchLink>; Tabby Therapeutics, Watertown, MA, United States.<br /><searchLink fieldCode="AU" term="%22Kindschuh+M%22">Kindschuh M</searchLink>; Tabby Therapeutics, Watertown, MA, United States.<br /><searchLink fieldCode="AU" term="%22Fung+J%22">Fung J</searchLink>; Tabby Therapeutics, Watertown, MA, United States.<br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; ElevateBio, Waltham, MA, United States.<br /><searchLink fieldCode="AU" term="%22Klooster+I%22">Klooster I</searchLink>; ElevateBio, Waltham, MA, United States.<br /><searchLink fieldCode="AU" term="%22Kim+E%22">Kim E</searchLink>; ElevateBio, Waltham, MA, United States.<br /><searchLink fieldCode="AU" term="%22Roth+C%22">Roth C</searchLink>; Life Edit Therapeutics, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Vander+Oever+M%22">Vander Oever M</searchLink>; Life Edit Therapeutics, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Khan+B%22">Khan B</searchLink>; ElevateBio, Waltham, MA, United States.<br /><searchLink fieldCode="AU" term="%22Zelikson+N%22">Zelikson N</searchLink>; Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Vagima+Y%22">Vagima Y</searchLink>; Department of Biotechnology, Israel Institute for Biological Research, Ness Ziona, Israel.<br /><searchLink fieldCode="AU" term="%22Saribasak+H%22">Saribasak H</searchLink>; ElevateBio, Waltham, MA, United States.<br /><searchLink fieldCode="AU" term="%22Santry+L%22">Santry L</searchLink>; ElevateBio, Waltham, MA, United States.<br /><searchLink fieldCode="AU" term="%22Klapper+LN%22">Klapper LN</searchLink>; Tabby Therapeutics, Ness Ziona, Israel.<br /><searchLink fieldCode="AU" term="%22Hess+S%22">Hess S</searchLink>; Tabby Therapeutics, Ness Ziona, Israel.<br /><searchLink fieldCode="AU" term="%22Mooney+J%22">Mooney J</searchLink>; ElevateBio, Waltham, MA, United States.<br /><searchLink fieldCode="AU" term="%22Bublik+DR%22">Bublik DR</searchLink>; Tabby Therapeutics, Ness Ziona, Israel.<br /><searchLink fieldCode="AU" term="%22Laken+H%22">Laken H</searchLink>; Tabby Therapeutics, Watertown, MA, United States.<br /><searchLink fieldCode="AU" term="%22Barzel+A%22">Barzel A</searchLink>; Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Borden+P%22">Borden P</searchLink>; Life Edit Therapeutics, Durham, NC, United States.<br /><searchLink fieldCode="AU" term="%22Plewa+C%22">Plewa C</searchLink>; ElevateBio, Waltham, MA, United States.<br /><searchLink fieldCode="AU" term="%22Chadbourne+AM%22">Chadbourne AM</searchLink>; ElevateBio, Waltham, MA, United States.<br /><searchLink fieldCode="AU" term="%22Bridgen+D%22">Bridgen D</searchLink>; Tabby Therapeutics, Watertown, MA, United States.<br /><searchLink fieldCode="AU" term="%22Nahmad+AD%22">Nahmad AD</searchLink>; Tabby Therapeutics, Ness Ziona, Israel.; The Samueli Integrative Cancer Pioneering Institute, Petah Tikva, Israel.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2025 Jul 30; Vol. 16, pp. 1621222. <i>Date of Electronic Publication: </i>2025 Jul 30 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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        Text: English
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