Benzestrol Isomer Stereochemistry Determines the Distinct Estrogenic Activities and Conformations of the Eight Isomers When Bound to Estrogen Receptor α.
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| Title: | Benzestrol Isomer Stereochemistry Determines the Distinct Estrogenic Activities and Conformations of the Eight Isomers When Bound to Estrogen Receptor α. |
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| Authors: | Hou Y; Department of Chemistry and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States., Nwachukwu JC; Department of Immunology and Microbiology, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida 33458, United States., Carlson K; Department of Chemistry and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States., Kim SH; Department of Chemistry and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States., Angle S; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States., Jacobsen EN; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States., Woods T; School of Chemical Sciences, University of Illinois, Urbana, Illinois 61801, United States., Mateus SL; Department of Cancer Biology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 60153, United States., Fanning SW; Department of Cancer Biology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 60153, United States., Ziegler Y; Department of Molecular and Integrative Physiology and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States., Katzenellenbogen BS; Department of Molecular and Integrative Physiology and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States., Nettles KW; Department of Immunology and Microbiology, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida 33458, United States., Katzenellenbogen JA; Department of Chemistry and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States. |
| Source: | ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2025 Jul 09; Vol. 8 (8), pp. 2526-2535. Date of Electronic Publication: 2025 Jul 09 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101721411 Publication Model: eCollection Cited Medium: Internet ISSN: 2575-9108 (Electronic) Linking ISSN: 25759108 NLM ISO Abbreviation: ACS Pharmacol Transl Sci Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40810159 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Benzestrol Isomer Stereochemistry Determines the Distinct Estrogenic Activities and Conformations of the Eight Isomers When Bound to Estrogen Receptor α. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hou+Y%22">Hou Y</searchLink>; Department of Chemistry and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States.<br /><searchLink fieldCode="AU" term="%22Nwachukwu+JC%22">Nwachukwu JC</searchLink>; Department of Immunology and Microbiology, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida 33458, United States.<br /><searchLink fieldCode="AU" term="%22Carlson+K%22">Carlson K</searchLink>; Department of Chemistry and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States.<br /><searchLink fieldCode="AU" term="%22Kim+SH%22">Kim SH</searchLink>; Department of Chemistry and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States.<br /><searchLink fieldCode="AU" term="%22Angle+S%22">Angle S</searchLink>; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States.<br /><searchLink fieldCode="AU" term="%22Jacobsen+EN%22">Jacobsen EN</searchLink>; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States.<br /><searchLink fieldCode="AU" term="%22Woods+T%22">Woods T</searchLink>; School of Chemical Sciences, University of Illinois, Urbana, Illinois 61801, United States.<br /><searchLink fieldCode="AU" term="%22Mateus+SL%22">Mateus SL</searchLink>; Department of Cancer Biology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 60153, United States.<br /><searchLink fieldCode="AU" term="%22Fanning+SW%22">Fanning SW</searchLink>; Department of Cancer Biology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 60153, United States.<br /><searchLink fieldCode="AU" term="%22Ziegler+Y%22">Ziegler Y</searchLink>; Department of Molecular and Integrative Physiology and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States.<br /><searchLink fieldCode="AU" term="%22Katzenellenbogen+BS%22">Katzenellenbogen BS</searchLink>; Department of Molecular and Integrative Physiology and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States.<br /><searchLink fieldCode="AU" term="%22Nettles+KW%22">Nettles KW</searchLink>; Department of Immunology and Microbiology, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida 33458, United States.<br /><searchLink fieldCode="AU" term="%22Katzenellenbogen+JA%22">Katzenellenbogen JA</searchLink>; Department of Chemistry and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101721411%22">ACS pharmacology & translational science</searchLink> [ACS Pharmacol Transl Sci] 2025 Jul 09; Vol. 8 (8), pp. 2526-2535. <i>Date of Electronic Publication: </i>2025 Jul 09 (<i>Print Publication: </i>2025). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101721411 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2575-9108 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225759108%22">25759108 </searchLink><i>NLM ISO Abbreviation: </i>ACS Pharmacol Transl Sci <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40810159 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acsptsci.5c00117 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2526 Titles: – TitleFull: Benzestrol Isomer Stereochemistry Determines the Distinct Estrogenic Activities and Conformations of the Eight Isomers When Bound to Estrogen Receptor α. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hou Y – PersonEntity: Name: NameFull: Nwachukwu JC – PersonEntity: Name: NameFull: Carlson K – PersonEntity: Name: NameFull: Kim SH – PersonEntity: Name: NameFull: Angle S – PersonEntity: Name: NameFull: Jacobsen EN – PersonEntity: Name: NameFull: Woods T – PersonEntity: Name: NameFull: Mateus SL – PersonEntity: Name: NameFull: Fanning SW – PersonEntity: Name: NameFull: Ziegler Y – PersonEntity: Name: NameFull: Katzenellenbogen BS – PersonEntity: Name: NameFull: Nettles KW – PersonEntity: Name: NameFull: Katzenellenbogen JA IsPartOfRelationships: – BibEntity: Dates: – D: 09 M: 07 Text: 2025 Jul 09 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2575-9108 Numbering: – Type: volume Value: 8 – Type: issue Value: 8 Titles: – TitleFull: ACS pharmacology & translational science Type: main |
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