Benzestrol Isomer Stereochemistry Determines the Distinct Estrogenic Activities and Conformations of the Eight Isomers When Bound to Estrogen Receptor α.
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| Title: | Benzestrol Isomer Stereochemistry Determines the Distinct Estrogenic Activities and Conformations of the Eight Isomers When Bound to Estrogen Receptor α. |
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| Authors: | Hou Y; Department of Chemistry and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States., Nwachukwu JC; Department of Immunology and Microbiology, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida 33458, United States., Carlson K; Department of Chemistry and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States., Kim SH; Department of Chemistry and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States., Angle S; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States., Jacobsen EN; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States., Woods T; School of Chemical Sciences, University of Illinois, Urbana, Illinois 61801, United States., Mateus SL; Department of Cancer Biology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 60153, United States., Fanning SW; Department of Cancer Biology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 60153, United States., Ziegler Y; Department of Molecular and Integrative Physiology and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States., Katzenellenbogen BS; Department of Molecular and Integrative Physiology and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States., Nettles KW; Department of Immunology and Microbiology, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida 33458, United States., Katzenellenbogen JA; Department of Chemistry and Cancer Center, University of Illinois, Urbana, Illinois 61801, United States. |
| Source: | ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2025 Jul 09; Vol. 8 (8), pp. 2526-2535. Date of Electronic Publication: 2025 Jul 09 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101721411 Publication Model: eCollection Cited Medium: Internet ISSN: 2575-9108 (Electronic) Linking ISSN: 25759108 NLM ISO Abbreviation: ACS Pharmacol Transl Sci Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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