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Increased EThcD Efficiency on the Hybrid Orbitrap Excedion Pro Mass Analyzer Extends the Depth in Identification and Sequence Coverage of HLA Class I Immunopeptidomes.

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Title: Increased EThcD Efficiency on the Hybrid Orbitrap Excedion Pro Mass Analyzer Extends the Depth in Identification and Sequence Coverage of HLA Class I Immunopeptidomes.
Authors: Kessler AL; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, Netherlands; Netherlands Proteomics Center, Utrecht, Netherlands., Fort KL; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, Netherlands; Netherlands Proteomics Center, Utrecht, Netherlands; Thermo Fisher Scientific GmbH, Bremen, Germany., Resemann HC; Thermo Fisher Scientific GmbH, Bremen, Germany., Krüger P; Thermo Fisher Scientific GmbH, Bremen, Germany., Wang C; Thermo Fisher Scientific GmbH, Bremen, Germany., Koch H; Thermo Fisher Scientific GmbH, Bremen, Germany., Hauschild JP; Thermo Fisher Scientific GmbH, Bremen, Germany., Marino F; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, Netherlands; Netherlands Proteomics Center, Utrecht, Netherlands. Electronic address: f.marino@uu.nl., Heck AJR; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, Netherlands; Netherlands Proteomics Center, Utrecht, Netherlands. Electronic address: a.j.r.heck@uu.nl.
Source: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2025 Sep; Vol. 24 (9), pp. 101049. Date of Electronic Publication: 2025 Aug 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 101125647 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-9484 (Electronic) Linking ISSN: 15359476 NLM ISO Abbreviation: Mol Cell Proteomics Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1535-9484
DOI:10.1016/j.mcpro.2025.101049