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Increased EThcD Efficiency on the Hybrid Orbitrap Excedion Pro Mass Analyzer Extends the Depth in Identification and Sequence Coverage of HLA Class I Immunopeptidomes.

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Title: Increased EThcD Efficiency on the Hybrid Orbitrap Excedion Pro Mass Analyzer Extends the Depth in Identification and Sequence Coverage of HLA Class I Immunopeptidomes.
Authors: Kessler AL; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, Netherlands; Netherlands Proteomics Center, Utrecht, Netherlands., Fort KL; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, Netherlands; Netherlands Proteomics Center, Utrecht, Netherlands; Thermo Fisher Scientific GmbH, Bremen, Germany., Resemann HC; Thermo Fisher Scientific GmbH, Bremen, Germany., Krüger P; Thermo Fisher Scientific GmbH, Bremen, Germany., Wang C; Thermo Fisher Scientific GmbH, Bremen, Germany., Koch H; Thermo Fisher Scientific GmbH, Bremen, Germany., Hauschild JP; Thermo Fisher Scientific GmbH, Bremen, Germany., Marino F; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, Netherlands; Netherlands Proteomics Center, Utrecht, Netherlands. Electronic address: f.marino@uu.nl., Heck AJR; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, Netherlands; Netherlands Proteomics Center, Utrecht, Netherlands. Electronic address: a.j.r.heck@uu.nl.
Source: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2025 Sep; Vol. 24 (9), pp. 101049. Date of Electronic Publication: 2025 Aug 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 101125647 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-9484 (Electronic) Linking ISSN: 15359476 NLM ISO Abbreviation: Mol Cell Proteomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Increased EThcD Efficiency on the Hybrid Orbitrap Excedion Pro Mass Analyzer Extends the Depth in Identification and Sequence Coverage of HLA Class I Immunopeptidomes.
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  Data: <searchLink fieldCode="AU" term="%22Kessler+AL%22">Kessler AL</searchLink>; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, Netherlands; Netherlands Proteomics Center, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Fort+KL%22">Fort KL</searchLink>; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, Netherlands; Netherlands Proteomics Center, Utrecht, Netherlands; Thermo Fisher Scientific GmbH, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Resemann+HC%22">Resemann HC</searchLink>; Thermo Fisher Scientific GmbH, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Krüger+P%22">Krüger P</searchLink>; Thermo Fisher Scientific GmbH, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Thermo Fisher Scientific GmbH, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Koch+H%22">Koch H</searchLink>; Thermo Fisher Scientific GmbH, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Hauschild+JP%22">Hauschild JP</searchLink>; Thermo Fisher Scientific GmbH, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Marino+F%22">Marino F</searchLink>; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, Netherlands; Netherlands Proteomics Center, Utrecht, Netherlands. Electronic address: f.marino@uu.nl.<br /><searchLink fieldCode="AU" term="%22Heck+AJR%22">Heck AJR</searchLink>; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, Netherlands; Netherlands Proteomics Center, Utrecht, Netherlands. Electronic address: a.j.r.heck@uu.nl.
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  Data: <searchLink fieldCode="JN" term="%22101125647%22">Molecular & cellular proteomics : MCP</searchLink> [Mol Cell Proteomics] 2025 Sep; Vol. 24 (9), pp. 101049. <i>Date of Electronic Publication: </i>2025 Aug 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+for+Biochemistry+and+Molecular+Biology%22">Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101125647 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1535-9484 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215359476%22">15359476 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cell Proteomics <i>Subsets: </i>MEDLINE
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              Text: 2025 Sep
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