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Autoimmune origin for immune checkpoint inhibitor-diabetes revealed by deep immune phenotyping of the pancreas.

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Title: Autoimmune origin for immune checkpoint inhibitor-diabetes revealed by deep immune phenotyping of the pancreas.
Authors: Quandt Z; Department of Medicine, University of California San Francisco, San Francisco, California, USA Zoe.Quandt@ucsf.edu.; Diabetes Center, University of California San Francisco, San Francisco, California, USA., Young A; Diabetes Center, University of California San Francisco, San Francisco, California, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, Utah, USA., Barlow GL; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, California, USA., Smith JA; Diabetes Center, University of California San Francisco, San Francisco, California, USA., Kusmartseva I; Department of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, Florida, USA., Dong S; Diabetes Center, University of California San Francisco, San Francisco, California, USA., Shapiro MR; Department of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, Florida, USA., Kang JH; Diabetes Center, University of California San Francisco, San Francisco, California, USA., Felton JL; Department of Pediatrics, Division of Pediatric Endocrinology and the Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA., Nguyen VQ; Diabetes Center, University of California San Francisco, San Francisco, California, USA.; Department of Surgery, University of California San Francisco, San Francisco, California, USA., Szot G; Diabetes Center, University of California San Francisco, San Francisco, California, USA.; Department of Surgery, University of California San Francisco, San Francisco, California, USA., Hassoun AA; Department of Surgery, California Pacific Medical Center, San Francisco, California, USA.; Department of Surgery, Zheen International Hospital, Erbil, Iraq., Perdigoto AL; Department of Internal Medicine, Yale University, New Haven, Connecticut, USA.; Internal Medicine, VA Connecticut Healthcare System, West Haven, Connecticut, USA., Herold KC; Department of Internal Medicine, Yale University, New Haven, Connecticut, USA.; Department of Immunobiology, Yale University, New Haven, Connecticut, USA., Nolan G; Department of Pathology, Stanford University School of Medicine, Stanford, California, USA., Bollyky PL; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Brusko TM; Department of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, Florida, USA.; Department of Pediatrics, University of Florida, Gainesville, Florida, USA.; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida, USA., Nakayama M; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.; Barbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, Colorado, USA., Cooper S; Liver Center, University of California San Francisco, San Francisco, California, USA.; Division of General and Transplant Hepatology, California Pacific Medical Center, San Francisco, California, USA., Anderson MS; Department of Medicine, University of California San Francisco, San Francisco, California, USA.; Diabetes Center, University of California San Francisco, San Francisco, California, USA.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2025 Aug 14; Vol. 13 (8). Date of Electronic Publication: 2025 Aug 14.
Publication Type: Journal Article; Case Reports
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Autoimmune origin for immune checkpoint inhibitor-diabetes revealed by deep immune phenotyping of the pancreas.
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  Data: <searchLink fieldCode="AU" term="%22Quandt+Z%22">Quandt Z</searchLink>; Department of Medicine, University of California San Francisco, San Francisco, California, USA Zoe.Quandt@ucsf.edu.; Diabetes Center, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Young+A%22">Young A</searchLink>; Diabetes Center, University of California San Francisco, San Francisco, California, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Barlow+GL%22">Barlow GL</searchLink>; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.<br /><searchLink fieldCode="AU" term="%22Smith+JA%22">Smith JA</searchLink>; Diabetes Center, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Kusmartseva+I%22">Kusmartseva I</searchLink>; Department of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Dong+S%22">Dong S</searchLink>; Diabetes Center, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Shapiro+MR%22">Shapiro MR</searchLink>; Department of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Kang+JH%22">Kang JH</searchLink>; Diabetes Center, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Felton+JL%22">Felton JL</searchLink>; Department of Pediatrics, Division of Pediatric Endocrinology and the Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+VQ%22">Nguyen VQ</searchLink>; Diabetes Center, University of California San Francisco, San Francisco, California, USA.; Department of Surgery, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Szot+G%22">Szot G</searchLink>; Diabetes Center, University of California San Francisco, San Francisco, California, USA.; Department of Surgery, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Hassoun+AA%22">Hassoun AA</searchLink>; Department of Surgery, California Pacific Medical Center, San Francisco, California, USA.; Department of Surgery, Zheen International Hospital, Erbil, Iraq.<br /><searchLink fieldCode="AU" term="%22Perdigoto+AL%22">Perdigoto AL</searchLink>; Department of Internal Medicine, Yale University, New Haven, Connecticut, USA.; Internal Medicine, VA Connecticut Healthcare System, West Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Herold+KC%22">Herold KC</searchLink>; Department of Internal Medicine, Yale University, New Haven, Connecticut, USA.; Department of Immunobiology, Yale University, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Nolan+G%22">Nolan G</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.<br /><searchLink fieldCode="AU" term="%22Bollyky+PL%22">Bollyky PL</searchLink>; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.<br /><searchLink fieldCode="AU" term="%22Brusko+TM%22">Brusko TM</searchLink>; Department of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, Florida, USA.; Department of Pediatrics, University of Florida, Gainesville, Florida, USA.; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Nakayama+M%22">Nakayama M</searchLink>; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.; Barbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Cooper+S%22">Cooper S</searchLink>; Liver Center, University of California San Francisco, San Francisco, California, USA.; Division of General and Transplant Hepatology, California Pacific Medical Center, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+MS%22">Anderson MS</searchLink>; Department of Medicine, University of California San Francisco, San Francisco, California, USA.; Diabetes Center, University of California San Francisco, San Francisco, California, USA.
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  Data: <searchLink fieldCode="JN" term="%22101620585%22">Journal for immunotherapy of cancer</searchLink> [J Immunother Cancer] 2025 Aug 14; Vol. 13 (8). <i>Date of Electronic Publication: </i>2025 Aug 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BMJ+Publishing+Group+Ltd%22">BMJ Publishing Group Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101620585 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2051-1426 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220511426%22">20511426 </searchLink><i>NLM ISO Abbreviation: </i>J Immunother Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1136/jitc-2025-011818
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        Text: English
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              Text: 2025 Aug 14
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