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Systematic pegRNA design with PRIDICT2.0 and ePRIDICT for efficient prime editing.

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Title: Systematic pegRNA design with PRIDICT2.0 and ePRIDICT for efficient prime editing.
Authors: Mathis N; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland. nicolas.mathis@pharma.uzh.ch., Marquart KF; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Allam A; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Krauthammer M; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Schwank G; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland. schwank@pharma.uzh.ch.
Source: Nature protocols [Nat Protoc] 2026 Apr; Vol. 21 (4), pp. 1523-1543. Date of Electronic Publication: 2025 Aug 14.
Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101284307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-2799 (Electronic) Linking ISSN: 17502799 NLM ISO Abbreviation: Nat Protoc Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Mathis+N%22">Mathis N</searchLink>; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland. nicolas.mathis@pharma.uzh.ch.<br /><searchLink fieldCode="AU" term="%22Marquart+KF%22">Marquart KF</searchLink>; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Allam+A%22">Allam A</searchLink>; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Krauthammer+M%22">Krauthammer M</searchLink>; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schwank+G%22">Schwank G</searchLink>; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland. schwank@pharma.uzh.ch.
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  Data: <searchLink fieldCode="JN" term="%22101284307%22">Nature protocols</searchLink> [Nat Protoc] 2026 Apr; Vol. 21 (4), pp. 1523-1543. <i>Date of Electronic Publication: </i>2025 Aug 14.
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        Value: 10.1038/s41596-025-01244-7
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