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Increased autophagy activity suppresses hyperglycemia-related colorectal cancer tumorigenesis both in vitro and in vivo.

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Title: Increased autophagy activity suppresses hyperglycemia-related colorectal cancer tumorigenesis both in vitro and in vivo.
Authors: Lin PW; Master of Science Program in Tropical Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan., Liu YW; Master of Science Program in Tropical Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan., Chu ML; Master of Science Program in Tropical Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan., Chu CA; Department of Pathology, National Cheng Kung University Hospital Tainan, Taiwan., Lee CT; Department of Pathology, National Cheng Kung University Hospital Tainan, Taiwan.; Department of Pathology, National Cheng Kung University Hospital Dou-Liou Branch Douliou City, Yunlin County, Taiwan., Shih YH; Department of Anatomy, School of Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan., Lan SH; Department of Life Sciences and Institute of Genome Sciences, National Yang Ming Chiao Tung University Taipei, Taiwan., Wu SY; Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University Taipei, Taiwan., Chang HY; Department of Anatomy, School of Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan., Chen WC; Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital Kaohsiung, Taiwan., Wu IC; Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital Kaohsiung, Taiwan.; Center for Cancer Research, Kaohsiung Medical University Kaohsiung, Taiwan., Chen LT; Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital Kaohsiung, Taiwan.; Center for Cancer Research, Kaohsiung Medical University Kaohsiung, Taiwan., Huang MY; Center for Cancer Research, Kaohsiung Medical University Kaohsiung, Taiwan.; Department of Radiation Oncology, Kaohsiung Medical University Hospital, Kaohsiung Medical University Kaohsiung, Taiwan.; Department of Radiation Oncology, School of Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan., Wang JY; Center for Cancer Research, Kaohsiung Medical University Kaohsiung, Taiwan.; Division of Colorectal Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University Kaohsiung, Taiwan.; Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan., Lee YR; Master of Science Program in Tropical Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.; Department of Microbiology and Immunology, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.; Faculty of Post-Baccalaureate Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.; Center for Tropical Medicine and Infectious Disease, Kaohsiung Medical University Kaohsiung, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital Kaohsiung, Taiwan., Liu HS; Master of Science Program in Tropical Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.; Center for Cancer Research, Kaohsiung Medical University Kaohsiung, Taiwan.; Medical Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University Kaohsiung, Taiwan.
Source: American journal of cancer research [Am J Cancer Res] 2025 Jul 15; Vol. 15 (7), pp. 2949-2969. Date of Electronic Publication: 2025 Jul 15 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: e-Century Pub. Corp Country of Publication: United States NLM ID: 101549944 Publication Model: eCollection Cited Medium: Print ISSN: 2156-6976 (Print) Linking ISSN: 21566976 NLM ISO Abbreviation: Am J Cancer Res Subsets: PubMed not MEDLINE
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  Data: Increased autophagy activity suppresses hyperglycemia-related colorectal cancer tumorigenesis both in vitro and in vivo.
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  Data: <searchLink fieldCode="AU" term="%22Lin+PW%22">Lin PW</searchLink>; Master of Science Program in Tropical Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+YW%22">Liu YW</searchLink>; Master of Science Program in Tropical Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chu+ML%22">Chu ML</searchLink>; Master of Science Program in Tropical Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chu+CA%22">Chu CA</searchLink>; Department of Pathology, National Cheng Kung University Hospital Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+CT%22">Lee CT</searchLink>; Department of Pathology, National Cheng Kung University Hospital Tainan, Taiwan.; Department of Pathology, National Cheng Kung University Hospital Dou-Liou Branch Douliou City, Yunlin County, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shih+YH%22">Shih YH</searchLink>; Department of Anatomy, School of Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lan+SH%22">Lan SH</searchLink>; Department of Life Sciences and Institute of Genome Sciences, National Yang Ming Chiao Tung University Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+SY%22">Wu SY</searchLink>; Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+HY%22">Chang HY</searchLink>; Department of Anatomy, School of Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+WC%22">Chen WC</searchLink>; Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+IC%22">Wu IC</searchLink>; Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital Kaohsiung, Taiwan.; Center for Cancer Research, Kaohsiung Medical University Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+LT%22">Chen LT</searchLink>; Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital Kaohsiung, Taiwan.; Center for Cancer Research, Kaohsiung Medical University Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+MY%22">Huang MY</searchLink>; Center for Cancer Research, Kaohsiung Medical University Kaohsiung, Taiwan.; Department of Radiation Oncology, Kaohsiung Medical University Hospital, Kaohsiung Medical University Kaohsiung, Taiwan.; Department of Radiation Oncology, School of Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+JY%22">Wang JY</searchLink>; Center for Cancer Research, Kaohsiung Medical University Kaohsiung, Taiwan.; Division of Colorectal Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University Kaohsiung, Taiwan.; Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+YR%22">Lee YR</searchLink>; Master of Science Program in Tropical Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.; Department of Microbiology and Immunology, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.; Faculty of Post-Baccalaureate Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.; Center for Tropical Medicine and Infectious Disease, Kaohsiung Medical University Kaohsiung, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+HS%22">Liu HS</searchLink>; Master of Science Program in Tropical Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.; Center for Cancer Research, Kaohsiung Medical University Kaohsiung, Taiwan.; Medical Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University Kaohsiung, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101549944%22">American journal of cancer research</searchLink> [Am J Cancer Res] 2025 Jul 15; Vol. 15 (7), pp. 2949-2969. <i>Date of Electronic Publication: </i>2025 Jul 15 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22e-Century+Pub%2E+Corp%22">e-Century Pub. Corp </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101549944 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2156-6976 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221566976%22">21566976 </searchLink><i>NLM ISO Abbreviation: </i>Am J Cancer Res <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.62347/XSRQ4118
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        Text: English
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      – TitleFull: Increased autophagy activity suppresses hyperglycemia-related colorectal cancer tumorigenesis both in vitro and in vivo.
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              Text: 2025 Jul 15
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