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Development and validation of an interpretable machine learning model for retrospective identification of suspected infection for sepsis surveillance: a multicentre cohort study.

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Title: Development and validation of an interpretable machine learning model for retrospective identification of suspected infection for sepsis surveillance: a multicentre cohort study.
Authors: Tuinte RAM; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands., Smolenaers LPJ; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.; Tilburg School of Economics and Management, Tilburg University, the Netherlands.; AethiQs B.V., the Netherlands., Knoop BT; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands., Föhse K; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands., van der Aart TJ; Department of Acute Care, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Bouma HR; Department of Acute Care, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Clinical Pharmacy & Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Netea MG; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Immunology and Metabolism, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany., Van Deun K; Department of Methodology & Statistics, Tilburg University, the Netherlands., Ten Oever J; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands., Hoogerwerf JJ; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
Source: EClinicalMedicine [EClinicalMedicine] 2025 Aug 08; Vol. 87, pp. 103401. Date of Electronic Publication: 2025 Aug 08 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: The Lancet Country of Publication: England NLM ID: 101733727 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-5370 (Electronic) Linking ISSN: 25895370 NLM ISO Abbreviation: EClinicalMedicine Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Tuinte+RAM%22">Tuinte RAM</searchLink>; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Smolenaers+LPJ%22">Smolenaers LPJ</searchLink>; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.; Tilburg School of Economics and Management, Tilburg University, the Netherlands.; AethiQs B.V., the Netherlands.<br /><searchLink fieldCode="AU" term="%22Knoop+BT%22">Knoop BT</searchLink>; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Föhse+K%22">Föhse K</searchLink>; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Aart+TJ%22">van der Aart TJ</searchLink>; Department of Acute Care, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bouma+HR%22">Bouma HR</searchLink>; Department of Acute Care, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Clinical Pharmacy & Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Netea+MG%22">Netea MG</searchLink>; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Immunology and Metabolism, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Van+Deun+K%22">Van Deun K</searchLink>; Department of Methodology & Statistics, Tilburg University, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ten+Oever+J%22">Ten Oever J</searchLink>; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Hoogerwerf+JJ%22">Hoogerwerf JJ</searchLink>; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Radboud Community for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
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              Text: 2025 Aug 08
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