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SEC61B regulates calcium flux and platelet hyperreactivity in diabetes.

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Title: SEC61B regulates calcium flux and platelet hyperreactivity in diabetes.
Authors: Kong YX; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Institute of Haematology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.; Heart Research Institute, University of Sydney, Sydney, New South Wales, Australia., Rehan R; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.; Department of Cardiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia., Moreno CL; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; The Dr. John and Anne Chong Lab for Functional Genomics, University of Sydney, Sydney, New South Wales, Australia.; School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia., Madsen S; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia., Zhang Y; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; School of Mathematics and Statistics, The University of Sydney, Sydney, New South Wales, Australia.; Sydney Precision Data Science, The University of Sydney, Sydney, New South Wales, Australia.; School of Mathematics, Statistics, Chemistry and Physics, Murdoch University, Perth, Western Australia, Australia., Zhao H; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.; School of Medical Sciences, University of Sydney, Sydney, New South Wales, Australia., Qi M; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia., Houlahan CB; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.; Heart Research Institute, University of Sydney, Sydney, New South Wales, Australia., Cartland SP; Heart Research Institute, University of Sydney, Sydney, New South Wales, Australia.; Centre for Peripheral Artery Disease, Heart Research institute, Sydney, New South Wales, Australia., Robertshaw D; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia., Trang V; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia., Ong FJL; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia., Liu M; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia., Cheng E; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; School of Medical Sciences, University of Sydney, Sydney, New South Wales, Australia., Alwis I; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Heart Research Institute, University of Sydney, Sydney, New South Wales, Australia., Dupuy A; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.; School of Biomedical Engineering, Faculty of Engineering, University of Sydney, Sydney, New South Wales Australia., Cielesh M; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; School of Medical Sciences, University of Sydney, Sydney, New South Wales, Australia., Cooke KC; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia., Potter M; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia., Stöckli J; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia., Morahan G; Centre for Diabetes Research, Harry Perkins Institute of Medical Research, Nedlands, Western Australia, Australia.; Australian Centre for Accelerating Diabetes Innovations, Melbourne Medical School, The University of Melbourne, Parkville, Victoria, Australia., Kalev-Zylinska ML; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.; Department of Pathology and Laboratory Medicine, Haematology Laboratory, Auckland City Hospital, Auckland, New Zealand., Rondina MT; Molecular Medicine Program, Department of Internal Medicine, and Division of Hematology and Hematologic Malignancies, University of Utah, Salt Lake City, Utah, USA., Schulman S; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA., Yang JYH; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; School of Mathematics and Statistics, The University of Sydney, Sydney, New South Wales, Australia.; Sydney Precision Data Science, The University of Sydney, Sydney, New South Wales, Australia., Neely GG; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; The Dr. John and Anne Chong Lab for Functional Genomics, University of Sydney, Sydney, New South Wales, Australia.; School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia., Schoenwaelder SM; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Heart Research Institute, University of Sydney, Sydney, New South Wales, Australia., Jackson SP; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Heart Research Institute, University of Sydney, Sydney, New South Wales, Australia., James DE; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia.; School of Medical Sciences, University of Sydney, Sydney, New South Wales, Australia., Kavurma MM; Heart Research Institute, University of Sydney, Sydney, New South Wales, Australia.; Centre for Peripheral Artery Disease, Heart Research institute, Sydney, New South Wales, Australia., Hocking SL; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.; Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia., Twigg SM; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.; Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia., Weaver JC; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.; Department of Cardiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia., Larance M; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; School of Medical Sciences, University of Sydney, Sydney, New South Wales, Australia., Passam FH; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Institute of Haematology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.; Heart Research Institute, University of Sydney, Sydney, New South Wales, Australia.
Source: The Journal of clinical investigation [J Clin Invest] 2025 Aug 15; Vol. 135 (16). Date of Electronic Publication: 2025 Aug 15 (Print Publication: 2025).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
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Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.; Department of Pathology and Laboratory Medicine, Haematology Laboratory, Auckland City Hospital, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Rondina+MT%22">Rondina MT</searchLink>; Molecular Medicine Program, Department of Internal Medicine, and Division of Hematology and Hematologic Malignancies, University of Utah, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Schulman+S%22">Schulman S</searchLink>; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Yang+JYH%22">Yang JYH</searchLink>; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; School of Mathematics and Statistics, The University of Sydney, Sydney, New South Wales, Australia.; Sydney Precision Data Science, The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Neely+GG%22">Neely GG</searchLink>; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; The Dr. John and Anne Chong Lab for Functional Genomics, University of Sydney, Sydney, New South Wales, Australia.; School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Schoenwaelder+SM%22">Schoenwaelder SM</searchLink>; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Heart Research Institute, University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Jackson+SP%22">Jackson SP</searchLink>; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Heart Research Institute, University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22James+DE%22">James DE</searchLink>; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia.; 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