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A high-resolution, nanopore-based artificial intelligence assay for DNA replication stress in human cancer cells.

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Title: A high-resolution, nanopore-based artificial intelligence assay for DNA replication stress in human cancer cells.
Authors: Jones MJK; Frazer Institute, Faculty of Health, Medicine, and Behavioural Sciences, University of Queensland, Brisbane, QLD, Australia. mathew.jones@uq.edu.au.; School of Chemistry & Molecular Biosciences, University of Queensland, Brisbane, QLD, Australia. mathew.jones@uq.edu.au., Rai SK; Frazer Institute, Faculty of Health, Medicine, and Behavioural Sciences, University of Queensland, Brisbane, QLD, Australia., Pfuderer PL; Department of Pathology, University of Cambridge, Cambridge, UK.; Cancer Research UK Cambridge Centre, Li Ka Shing Centre, Robinson Way, Cambridge, UK., Bonfim-Melo A; Frazer Institute, Faculty of Health, Medicine, and Behavioural Sciences, University of Queensland, Brisbane, QLD, Australia., Pagan JK; School of Biomedical Sciences, The University of Queensland, Saint Lucia, QLD, Australia., Clarke PR; Frazer Institute, Faculty of Health, Medicine, and Behavioural Sciences, University of Queensland, Brisbane, QLD, Australia.; Institute for Biomedicine and Glycomics, Griffith University, Southport, QLD, Australia., Totañes FIG; Wellcome Sanger Institute, Cambridge, UK., Merrick CJ; Department of Pathology, University of Cambridge, Cambridge, UK., McClelland SE; Barts Cancer Institute, Queen Mary University of London, London, EC1M 6BQ, UK., Boemo MA; Department of Pathology, University of Cambridge, Cambridge, UK. mb915@cam.ac.uk.; Department of Genetics, University of Cambridge, Cambridge, CB2 3EH, UK. mb915@cam.ac.uk.
Source: Nature communications [Nat Commun] 2025 Aug 19; Vol. 16 (1), pp. 7732. Date of Electronic Publication: 2025 Aug 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Jones+MJK%22">Jones MJK</searchLink>; Frazer Institute, Faculty of Health, Medicine, and Behavioural Sciences, University of Queensland, Brisbane, QLD, Australia. mathew.jones@uq.edu.au.; School of Chemistry & Molecular Biosciences, University of Queensland, Brisbane, QLD, Australia. mathew.jones@uq.edu.au.<br /><searchLink fieldCode="AU" term="%22Rai+SK%22">Rai SK</searchLink>; Frazer Institute, Faculty of Health, Medicine, and Behavioural Sciences, University of Queensland, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Pfuderer+PL%22">Pfuderer PL</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK.; Cancer Research UK Cambridge Centre, Li Ka Shing Centre, Robinson Way, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Bonfim-Melo+A%22">Bonfim-Melo A</searchLink>; Frazer Institute, Faculty of Health, Medicine, and Behavioural Sciences, University of Queensland, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Pagan+JK%22">Pagan JK</searchLink>; School of Biomedical Sciences, The University of Queensland, Saint Lucia, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Clarke+PR%22">Clarke PR</searchLink>; Frazer Institute, Faculty of Health, Medicine, and Behavioural Sciences, University of Queensland, Brisbane, QLD, Australia.; Institute for Biomedicine and Glycomics, Griffith University, Southport, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Totañes+FIG%22">Totañes FIG</searchLink>; Wellcome Sanger Institute, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Merrick+CJ%22">Merrick CJ</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22McClelland+SE%22">McClelland SE</searchLink>; Barts Cancer Institute, Queen Mary University of London, London, EC1M 6BQ, UK.<br /><searchLink fieldCode="AU" term="%22Boemo+MA%22">Boemo MA</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK. mb915@cam.ac.uk.; Department of Genetics, University of Cambridge, Cambridge, CB2 3EH, UK. mb915@cam.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Aug 19; Vol. 16 (1), pp. 7732. <i>Date of Electronic Publication: </i>2025 Aug 19.
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