Novel Predictive Spatial Biomarker in Non-Small Cell Lung Carcinoma: The Diversity of Niches Unlocking Treatment Sensitivity (DONUTS).
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| Title: | Novel Predictive Spatial Biomarker in Non-Small Cell Lung Carcinoma: The Diversity of Niches Unlocking Treatment Sensitivity (DONUTS). |
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| Authors: | Cottrell TR; Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada., Roskes JS; Department of Physics & Astronomy, Johns Hopkins University, Baltimore, MD, USA.; The Institute for Data Intensive Engineering and Science, Johns Hopkins University, Baltimore, MD, USA.; The Mark Foundation for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD, USA., Fotheringham M; Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada., Cohen E; Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada., Zhang B; Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Engle LL; Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA.; The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, MD, USA.; The Mark Foundation for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD, USA., Wang D; Department of Pathology, Johns Hopkins University, Baltimore, MD, USA., Will E; Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA., Sunshine JC; Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.; Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA.; The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, MD, USA., Jimenez-Sanchez D; Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA.; The Mark Foundation for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD, USA., Zeng Z; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.; The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, MD, USA., Caushi JX; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA., Zhang J; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA., D'Amiano NM; Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA., Deutsch JS; Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.; Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA., Uttam S; Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada., Pirie K; Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada., Vlaminck D; Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada., Mataj M; Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada., Radwan E; Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada., Fiorante A; Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada., Espinosa N; Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada., Popa T; Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada., Ogurtsova A; Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA.; The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, MD, USA., Soto-Diaz S; Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA.; The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, MD, USA., Eminizer M; Department of Physics & Astronomy, Johns Hopkins University, Baltimore, MD, USA.; Data Science and AI Institute, Johns Hopkins University, Baltimore, MD, USA., Tabrisky S; Department of Physics & Astronomy, Johns Hopkins University, Baltimore, MD, USA.; The Institute for Data Intensive Engineering and Science, Johns Hopkins University, Baltimore, MD, USA., Jorquera A; Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA., Skidmore J; Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA., Medvedev D; Department of Physics & Astronomy, Johns Hopkins University, Baltimore, MD, USA., Chaft JE; Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA., Brahmer JR; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.; The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, MD, USA., Conroy M; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA., Reuss JE; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA., Danilova L; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA., Ji H; Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Forde PM; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA., Pardoll DM; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.; The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, MD, USA.; The Mark Foundation for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD, USA., Smith KN; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.; The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, MD, USA.; The Mark Foundation for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD, USA., Green BF; Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA.; Department of Physics & Astronomy, Johns Hopkins University, Baltimore, MD, USA., Szalay AS; Department of Physics & Astronomy, Johns Hopkins University, Baltimore, MD, USA.; The Institute for Data Intensive Engineering and Science, Johns Hopkins University, Baltimore, MD, USA.; The Mark Foundation for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD, USA., Taube JM; Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.; Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA.; The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, MD, USA.; The Mark Foundation for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2025 Sep 24. Date of Electronic Publication: 2025 Sep 24. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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