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Intracortical microstimulation in humans: a decade of safety and efficacy.

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Title: Intracortical microstimulation in humans: a decade of safety and efficacy.
Authors: Greenspon CM; Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL, USA., Hobbs TG; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA., Verbaarschot C; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Neurological Surgery, University of Texas-Southwestern, Dallas, TX, USA.; Department of Biomedical Engineering, University of Texas-Southwestern, Dallas, TX, USA.; Peter O'Donnell Jr. Brain Institute, UT Southwestern, Dallas., Alamri AH; Committee on Computational Neuroscience, University of Chicago, Chicago, IL, USA., Shelchkova ND; Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL, USA., Lienkämper R; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA., Ye J; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Neuroscience Institute, Carnegie Mellon University, PA, US., Simpson TW; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA., Weiss JM; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA., Weir DM; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA., Harrington DE; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA., Van Driesche A; Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL, USA., Satzer D; Department of Neurological Surgery, University of Chicago, Chicago, IL, USA., Valle G; Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL, USA.; Department of Electrical Engineering, Chalmers University of Technology, Göteborg, Sweden., Miller LE; Department of Neuroscience, Northwestern University, Chicago, IL, USA.; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.; Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL, USA.; Shirley Ryan Ability Lab, Chicago, IL, USA., Hatsopoulos NG; Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL, USA.; Neuroscience Institute, University of Chicago, IL, USA., Gonzalez-Martinez J; Department of Neurosurgery, University of Pittsburgh, Pittsburgh, PA, USA., Warnke PC; Department of Neurological Surgery, University of Chicago, Chicago, IL, USA.; Neuroscience Institute, University of Chicago, IL, USA., Downey JE; Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL, USA., Boninger ML; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA., Collinger JL; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA., Gaunt RA; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2025 Aug 13. Date of Electronic Publication: 2025 Aug 13.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Intracortical microstimulation in humans: a decade of safety and efficacy.
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  Data: <searchLink fieldCode="AU" term="%22Greenspon+CM%22">Greenspon CM</searchLink>; Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Hobbs+TG%22">Hobbs TG</searchLink>; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Verbaarschot+C%22">Verbaarschot C</searchLink>; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Neurological Surgery, University of Texas-Southwestern, Dallas, TX, USA.; Department of Biomedical Engineering, University of Texas-Southwestern, Dallas, TX, USA.; Peter O'Donnell Jr. Brain Institute, UT Southwestern, Dallas.<br /><searchLink fieldCode="AU" term="%22Alamri+AH%22">Alamri AH</searchLink>; Committee on Computational Neuroscience, University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Shelchkova+ND%22">Shelchkova ND</searchLink>; Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Lienkämper+R%22">Lienkämper R</searchLink>; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ye+J%22">Ye J</searchLink>; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Neuroscience Institute, Carnegie Mellon University, PA, US.<br /><searchLink fieldCode="AU" term="%22Simpson+TW%22">Simpson TW</searchLink>; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Weiss+JM%22">Weiss JM</searchLink>; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Weir+DM%22">Weir DM</searchLink>; 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Department of Neuroscience, Northwestern University, Chicago, IL, USA.; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.; Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL, USA.; Shirley Ryan Ability Lab, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Hatsopoulos+NG%22">Hatsopoulos NG</searchLink>; Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL, USA.; Neuroscience Institute, University of Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Martinez+J%22">Gonzalez-Martinez J</searchLink>; Department of Neurosurgery, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Warnke+PC%22">Warnke PC</searchLink>; Department of Neurological Surgery, University of Chicago, Chicago, IL, USA.; Neuroscience Institute, University of Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Downey+JE%22">Downey JE</searchLink>; Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Boninger+ML%22">Boninger ML</searchLink>; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Collinger+JL%22">Collinger JL</searchLink>; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Gaunt+RA%22">Gaunt RA</searchLink>; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA.
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