A database study of the safety and effectiveness of daily growth hormone in treating more than 80,000 children with growth disorders worldwide: a plain language summary of publication.

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Title: A database study of the safety and effectiveness of daily growth hormone in treating more than 80,000 children with growth disorders worldwide: a plain language summary of publication.
Authors: Maghnie M; Department of Pediatrics, IRCCS Giannina Gaslini, Genova, Italy.; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy., Ranke MB; Department of Pediatric Endocrinology, University Children's Hospital, Tübingen, Germany., Geffner ME; Department of Pediatrics, The Saban Research Institute, Children's Hospital Los Angeles, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Vlachopapadopoulou E; Department of Endocrinology, Growth and Development, Children's Hospital P. & A. Kyriakou, Athens, Greece., Ibáñez L; Department of Endocrinology and Endocrinologia Metabòlica, Institut de Recerca Sant Joan de Déu (Department of Endocrinology and Metabolic Endocrinology, Institut de Recerca Sant Joan de Déu), University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III (Biomedical Research Center for Diabetes and Associated Metabolic Diseases, Carlos III Health Institute), Madrid, Spain., Carlsson M; Inflammation and Immunology, Pfizer Inc., New York, NY, USA., Cutfield W; Paediatric Endocrinology, Liggins Institute, University of Auckland, Auckland, New Zealand., Rooman R; PendoCon, Putte, Belgium., Gomez R; Pfizer Biopharmaceuticals Group, Pfizer Pte Ltd, Singapore, Singapore., Wajnrajch MP; Rare Disease, Biopharmaceuticals, Pfizer, New York, NY, USA.; Department of Pediatrics, New York University Grossman School of Medicine, New York, NY, USA., Linglart A; Department of Pediatric Endocrinology and Diabetology for Children, AP-HP, Bicêtre Paris Saclay, Le Kremlin Bicêtre (Bicêtre Paris Saclay, The Kremlin Bicêtre), France.; APHP, Reference Center for Rare Diseases of Calcium and Phosphate Metabolism, and Filière OSCAR, endo ERN and ERN BOND, Paris, France., Stawerska R; Department of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital-Research Institute, Lodz, Poland.; Department of Paediatric Endocrinology, Medical University of Lodz, Lodz, Poland., Clayton PE; Developmental Biology and Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Darendeliler F; Pediatric Endocrinology Unit, İstanbul Faculty of Medicine, İstanbul, Turkey., Hokken-Koelega ACS; Department of Pediatrics, Subdivision of Endocrinology, Erasmus University Medical Center, Rotterdam, The Netherlands., Horikawa R; Division of Endocrinology and Metabolism, National Center for Child Health and Development, Tokyo, Japan., Tanaka T; Tanaka Growth Clinic, Tokyo, Japan., Dörr HG; Division of Pediatric Endocrinology, Department of Pediatrics and Adolescent Medicine, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany., Polak M; Paediatric Endocrinology, Gynaecology and Diabetology Department, Hôpital Universitaire Necker Enfants Malades, Université de Paris Cité (Necker Children's University Hospital, University of Paris City), Paris, France., Grimberg A; Division of Pediatric Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Source: Therapeutic advances in endocrinology and metabolism [Ther Adv Endocrinol Metab] 2025 Aug 17; Vol. 16, pp. 20420188251345556. Date of Electronic Publication: 2025 Aug 17 (Print Publication: 2025).
Publication Type: Journal Article; Review
Journal Info: Publisher: Sage Publication Country of Publication: United States NLM ID: 101532143 Publication Model: eCollection Cited Medium: Print ISSN: 2042-0188 (Print) Linking ISSN: 20420188 NLM ISO Abbreviation: Ther Adv Endocrinol Metab Subsets: PubMed not MEDLINE
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  Data: A database study of the safety and effectiveness of daily growth hormone in treating more than 80,000 children with growth disorders worldwide: a plain language summary of publication.
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  Data: <searchLink fieldCode="AU" term="%22Maghnie+M%22">Maghnie M</searchLink>; Department of Pediatrics, IRCCS Giannina Gaslini, Genova, Italy.; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Ranke+MB%22">Ranke MB</searchLink>; Department of Pediatric Endocrinology, University Children's Hospital, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Geffner+ME%22">Geffner ME</searchLink>; Department of Pediatrics, The Saban Research Institute, Children's Hospital Los Angeles, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Vlachopapadopoulou+E%22">Vlachopapadopoulou E</searchLink>; Department of Endocrinology, Growth and Development, Children's Hospital P. & A. Kyriakou, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Ibáñez+L%22">Ibáñez L</searchLink>; Department of Endocrinology and Endocrinologia Metabòlica, Institut de Recerca Sant Joan de Déu (Department of Endocrinology and Metabolic Endocrinology, Institut de Recerca Sant Joan de Déu), University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III (Biomedical Research Center for Diabetes and Associated Metabolic Diseases, Carlos III Health Institute), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Carlsson+M%22">Carlsson M</searchLink>; Inflammation and Immunology, Pfizer Inc., New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cutfield+W%22">Cutfield W</searchLink>; Paediatric Endocrinology, Liggins Institute, University of Auckland, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Rooman+R%22">Rooman R</searchLink>; PendoCon, Putte, Belgium.<br /><searchLink fieldCode="AU" term="%22Gomez+R%22">Gomez R</searchLink>; Pfizer Biopharmaceuticals Group, Pfizer Pte Ltd, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wajnrajch+MP%22">Wajnrajch MP</searchLink>; Rare Disease, Biopharmaceuticals, Pfizer, New York, NY, USA.; Department of Pediatrics, New York University Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Linglart+A%22">Linglart A</searchLink>; Department of Pediatric Endocrinology and Diabetology for Children, AP-HP, Bicêtre Paris Saclay, Le Kremlin Bicêtre (Bicêtre Paris Saclay, The Kremlin Bicêtre), France.; APHP, Reference Center for Rare Diseases of Calcium and Phosphate Metabolism, and Filière OSCAR, endo ERN and ERN BOND, Paris, France.<br /><searchLink fieldCode="AU" term="%22Stawerska+R%22">Stawerska R</searchLink>; Department of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital-Research Institute, Lodz, Poland.; Department of Paediatric Endocrinology, Medical University of Lodz, Lodz, Poland.<br /><searchLink fieldCode="AU" term="%22Clayton+PE%22">Clayton PE</searchLink>; Developmental Biology and Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Darendeliler+F%22">Darendeliler F</searchLink>; Pediatric Endocrinology Unit, İstanbul Faculty of Medicine, İstanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Hokken-Koelega+ACS%22">Hokken-Koelega ACS</searchLink>; Department of Pediatrics, Subdivision of Endocrinology, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Horikawa+R%22">Horikawa R</searchLink>; Division of Endocrinology and Metabolism, National Center for Child Health and Development, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+T%22">Tanaka T</searchLink>; Tanaka Growth Clinic, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Dörr+HG%22">Dörr HG</searchLink>; Division of Pediatric Endocrinology, Department of Pediatrics and Adolescent Medicine, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Polak+M%22">Polak M</searchLink>; Paediatric Endocrinology, Gynaecology and Diabetology Department, Hôpital Universitaire Necker Enfants Malades, Université de Paris Cité (Necker Children's University Hospital, University of Paris City), Paris, France.<br /><searchLink fieldCode="AU" term="%22Grimberg+A%22">Grimberg A</searchLink>; Division of Pediatric Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
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