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Small vessel dysfunction at 7T MRI locally predicts white matter damage progression in CADASIL.

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Title: Small vessel dysfunction at 7T MRI locally predicts white matter damage progression in CADASIL.
Authors: Pham SD; Translational Neuroimaging Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht University, the Netherlands., van den Brink H; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, the Netherlands.; J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Kopczak A; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany., Vlegels N; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, the Netherlands.; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany., De Luca A; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, the Netherlands.; Image Sciences Institute, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Gesierich B; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany.; Medical Image Analysis Center (MIAC), University of Basel, Basel, Switzerland., Stringer MS; Brain Research Imaging Center, Center for Clinical Brain Sciences, UK Dementia Institute Center at the University of Edinburgh, Edinburgh, UK., Thrippleton MJ; Brain Research Imaging Center, Center for Clinical Brain Sciences, UK Dementia Institute Center at the University of Edinburgh, Edinburgh, UK., Wardlaw JM; Brain Research Imaging Center, Center for Clinical Brain Sciences, UK Dementia Institute Center at the University of Edinburgh, Edinburgh, UK., Bhogal AA; Translational Neuroimaging Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht University, the Netherlands., Dieleman N; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, the Netherlands., Zwanenburg JJ; Translational Neuroimaging Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht University, the Netherlands., Duering M; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany.; Medical Image Analysis Center (MIAC), University of Basel, Basel, Switzerland., Biessels GJ; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, the Netherlands., Siero JC; Translational Neuroimaging Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht University, the Netherlands.; Spinoza Centre for Neuroimaging, Amsterdam, Netherlands.
Source: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2026 Feb; Vol. 46 (2), pp. 521-533. Date of Electronic Publication: 2025 Aug 20.
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Small vessel dysfunction at 7T MRI locally predicts white matter damage progression in CADASIL.
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  Data: <searchLink fieldCode="AU" term="%22Pham+SD%22">Pham SD</searchLink>; Translational Neuroimaging Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht University, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Brink+H%22">van den Brink H</searchLink>; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, the Netherlands.; J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kopczak+A%22">Kopczak A</searchLink>; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Vlegels+N%22">Vlegels N</searchLink>; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, the Netherlands.; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22De+Luca+A%22">De Luca A</searchLink>; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, the Netherlands.; Image Sciences Institute, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gesierich+B%22">Gesierich B</searchLink>; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany.; Medical Image Analysis Center (MIAC), University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Stringer+MS%22">Stringer MS</searchLink>; Brain Research Imaging Center, Center for Clinical Brain Sciences, UK Dementia Institute Center at the University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Thrippleton+MJ%22">Thrippleton MJ</searchLink>; Brain Research Imaging Center, Center for Clinical Brain Sciences, UK Dementia Institute Center at the University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Wardlaw+JM%22">Wardlaw JM</searchLink>; Brain Research Imaging Center, Center for Clinical Brain Sciences, UK Dementia Institute Center at the University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Bhogal+AA%22">Bhogal AA</searchLink>; Translational Neuroimaging Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht University, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Dieleman+N%22">Dieleman N</searchLink>; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Zwanenburg+JJ%22">Zwanenburg JJ</searchLink>; Translational Neuroimaging Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht University, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Duering+M%22">Duering M</searchLink>; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany.; Medical Image Analysis Center (MIAC), University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Biessels+GJ%22">Biessels GJ</searchLink>; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Siero+JC%22">Siero JC</searchLink>; Translational Neuroimaging Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht University, the Netherlands.; Spinoza Centre for Neuroimaging, Amsterdam, Netherlands.
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