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Macrophage TBK1 signaling drives the development and outgrowth of breast cancer brain metastasis.

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Title: Macrophage TBK1 signaling drives the development and outgrowth of breast cancer brain metastasis.
Authors: Khan F; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611., Liu Y; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611., Whitfield D; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., Pang L; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611., Ali H; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611., Huang Y; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611., Zhou F; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611., Hagan RS; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Frenis K; Department of Hematology, Boston Children's Hospital, Boston, MA 02115., Rowe RG; Department of Hematology, Boston Children's Hospital, Boston, MA 02115.; Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA 02115., Chen P; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.; Case Comprehensive Cancer Center, Cleveland, OH 44106.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Aug 26; Vol. 122 (34), pp. e2420793122. Date of Electronic Publication: 2025 Aug 20.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Khan+F%22">Khan F</searchLink>; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.<br /><searchLink fieldCode="AU" term="%22Whitfield+D%22">Whitfield D</searchLink>; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.<br /><searchLink fieldCode="AU" term="%22Pang+L%22">Pang L</searchLink>; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.<br /><searchLink fieldCode="AU" term="%22Ali+H%22">Ali H</searchLink>; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.<br /><searchLink fieldCode="AU" term="%22Zhou+F%22">Zhou F</searchLink>; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.<br /><searchLink fieldCode="AU" term="%22Hagan+RS%22">Hagan RS</searchLink>; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.<br /><searchLink fieldCode="AU" term="%22Frenis+K%22">Frenis K</searchLink>; Department of Hematology, Boston Children's Hospital, Boston, MA 02115.<br /><searchLink fieldCode="AU" term="%22Rowe+RG%22">Rowe RG</searchLink>; Department of Hematology, Boston Children's Hospital, Boston, MA 02115.; Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA 02115.<br /><searchLink fieldCode="AU" term="%22Chen+P%22">Chen P</searchLink>; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.; Case Comprehensive Cancer Center, Cleveland, OH 44106.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2025 Aug 26; Vol. 122 (34), pp. e2420793122. <i>Date of Electronic Publication: </i>2025 Aug 20.
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