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An in vitro evaluation of common botanical extracts on carboxylesterase 1 catalytic activity.

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Title: An in vitro evaluation of common botanical extracts on carboxylesterase 1 catalytic activity.
Authors: Melchert PW; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, Florida. Electronic address: melchertphilip@ufl.edu., Zhang Q; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, Florida., Raeuscher JM; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, Florida., Gurley BJ; Natural Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, Oxford, Mississippi., Markowitz JS; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, Florida; Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida.
Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2025 Sep; Vol. 53 (9), pp. 100129. Date of Electronic Publication: 2025 Jul 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Melchert+PW%22">Melchert PW</searchLink>; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, Florida. Electronic address: melchertphilip@ufl.edu.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, Florida.<br /><searchLink fieldCode="AU" term="%22Raeuscher+JM%22">Raeuscher JM</searchLink>; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, Florida.<br /><searchLink fieldCode="AU" term="%22Gurley+BJ%22">Gurley BJ</searchLink>; Natural Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, Oxford, Mississippi.<br /><searchLink fieldCode="AU" term="%22Markowitz+JS%22">Markowitz JS</searchLink>; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, Florida; Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida.
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        Value: 10.1016/j.dmd.2025.100129
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        Text: English
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              Text: 2025 Sep
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