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Accelerated cGMP production of near-native HIV-1 Env trimers following electroporation transfection and immunogenicity analysis.

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Title: Accelerated cGMP production of near-native HIV-1 Env trimers following electroporation transfection and immunogenicity analysis.
Authors: Bale S; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Gustchina E; ABL Inc., Rockville, MD, USA., Guenaga J; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; International AIDS Vaccine Initiative, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Ayala V; ABL Inc., Rockville, MD, USA., Lee WH; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, USA., Ozorowski G; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, USA., Whitney S; ABL Inc., Rockville, MD, USA., Wilson R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Baboo S; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA., Diedrich JK; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA., Doyle ED; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Hudacik L; ABL Inc., Rockville, MD, USA., Ben-Akiva E; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA., Rodrigues KA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA., Irvine DJ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Howard Hughes Medical Institute, 4000 Jones Bridge Rd., Chevy Chase, MD, USA., Yates JR 3rd; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA., Paulson JC; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Fouts T; ABL Inc., Rockville, MD, USA. timothy.fouts@ablinc.com., Wyatt RT; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. wyatt@scripps.edu.; International AIDS Vaccine Initiative, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA. wyatt@scripps.edu.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA. wyatt@scripps.edu.
Source: NPJ vaccines [NPJ Vaccines] 2025 Aug 20; Vol. 10 (1), pp. 198. Date of Electronic Publication: 2025 Aug 20.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines Subsets: PubMed not MEDLINE
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  Data: Accelerated cGMP production of near-native HIV-1 Env trimers following electroporation transfection and immunogenicity analysis.
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  Data: <searchLink fieldCode="AU" term="%22Bale+S%22">Bale S</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gustchina+E%22">Gustchina E</searchLink>; ABL Inc., Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Guenaga+J%22">Guenaga J</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; International AIDS Vaccine Initiative, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ayala+V%22">Ayala V</searchLink>; ABL Inc., Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lee+WH%22">Lee WH</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, USA.<br /><searchLink fieldCode="AU" term="%22Ozorowski+G%22">Ozorowski G</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, USA.<br /><searchLink fieldCode="AU" term="%22Whitney+S%22">Whitney S</searchLink>; ABL Inc., Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+R%22">Wilson R</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Baboo+S%22">Baboo S</searchLink>; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Diedrich+JK%22">Diedrich JK</searchLink>; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Doyle+ED%22">Doyle ED</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hudacik+L%22">Hudacik L</searchLink>; ABL Inc., Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ben-Akiva+E%22">Ben-Akiva E</searchLink>; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rodrigues+KA%22">Rodrigues KA</searchLink>; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Irvine+DJ%22">Irvine DJ</searchLink>; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Howard Hughes Medical Institute, 4000 Jones Bridge Rd., Chevy Chase, MD, USA.<br /><searchLink fieldCode="AU" term="%22Yates+JR+3rd%22">Yates JR 3rd</searchLink>; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Paulson+JC%22">Paulson JC</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ward+AB%22">Ward AB</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, USA.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Fouts+T%22">Fouts T</searchLink>; ABL Inc., Rockville, MD, USA. timothy.fouts@ablinc.com.<br /><searchLink fieldCode="AU" term="%22Wyatt+RT%22">Wyatt RT</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. wyatt@scripps.edu.; International AIDS Vaccine Initiative, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA. wyatt@scripps.edu.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA. wyatt@scripps.edu.
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  Data: <searchLink fieldCode="JN" term="%22101699863%22">NPJ vaccines</searchLink> [NPJ Vaccines] 2025 Aug 20; Vol. 10 (1), pp. 198. <i>Date of Electronic Publication: </i>2025 Aug 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature+in+partnership+with+the+Sealy+Center+for+Vaccine+Development%22">Springer Nature in partnership with the Sealy Center for Vaccine Development </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101699863 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-0105 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220590105%22">20590105 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Vaccines <i>Subsets: </i>PubMed not MEDLINE
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