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Integration of biomimetic organoid-on-chip and 2D models advances the mechanistic Understanding of STEAP3-mediated regulation in intestinal viral infection.

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Title: Integration of biomimetic organoid-on-chip and 2D models advances the mechanistic Understanding of STEAP3-mediated regulation in intestinal viral infection.
Authors: Chen YW; Research and Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404332, Taiwan.; Department of Bioinformatics and Medical Engineering, Asia University, Taichung, 41354, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan., Chiang HJ; Research Center for Emerging Viral Infections, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan.; Department of Medical Biotechnology & Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan., Liu KT; Research Center for Emerging Viral Infections, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan.; Department of Microbiology and Immunology, School of Medicine, Stanford University, Stanford, CA, 94305, U.S., Kao CW; Research and Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404332, Taiwan., Xie SR; Research and Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404332, Taiwan., Su CM; Research and Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404332, Taiwan., Shih YY; Research and Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404332, Taiwan. ami8824@gmail.com.; Research Center for Emerging Viral Infections, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan. ami8824@gmail.com.
Source: Scientific reports [Sci Rep] 2025 Aug 20; Vol. 15 (1), pp. 30582. Date of Electronic Publication: 2025 Aug 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integration of biomimetic organoid-on-chip and 2D models advances the mechanistic Understanding of STEAP3-mediated regulation in intestinal viral infection.
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  Data: <searchLink fieldCode="AU" term="%22Chen+YW%22">Chen YW</searchLink>; Research and Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404332, Taiwan.; Department of Bioinformatics and Medical Engineering, Asia University, Taichung, 41354, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiang+HJ%22">Chiang HJ</searchLink>; Research Center for Emerging Viral Infections, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan.; Department of Medical Biotechnology & Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+KT%22">Liu KT</searchLink>; Research Center for Emerging Viral Infections, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan.; Department of Microbiology and Immunology, School of Medicine, Stanford University, Stanford, CA, 94305, U.S.<br /><searchLink fieldCode="AU" term="%22Kao+CW%22">Kao CW</searchLink>; Research and Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404332, Taiwan.<br /><searchLink fieldCode="AU" term="%22Xie+SR%22">Xie SR</searchLink>; Research and Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404332, Taiwan.<br /><searchLink fieldCode="AU" term="%22Su+CM%22">Su CM</searchLink>; Research and Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404332, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shih+YY%22">Shih YY</searchLink>; Research and Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404332, Taiwan. ami8824@gmail.com.; Research Center for Emerging Viral Infections, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan. ami8824@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2025 Aug 20; Vol. 15 (1), pp. 30582. <i>Date of Electronic Publication: </i>2025 Aug 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE
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              Text: 2025 Aug 20
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