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Early life adversity increases risk for chronic post-traumatic pain, data from humans and rodents.

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Title: Early life adversity increases risk for chronic post-traumatic pain, data from humans and rodents.
Authors: McKibben LA; Department of Anesthesiology, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Woolard A; Department of Anesthesiology, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.; Department of Genetics, Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., McLean SA; Department of Emergency Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.; Department of Psychiatry, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Zhao Y; Department of Anesthesiology, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Verma T; Department of Anesthesiology, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Mickelson J; Department of Anesthesiology, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Lu H; Department of Psychiatry, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Lobo J; Department of Anesthesiology, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., House SL; Department of Emergency Medicine, Washington University School of Medicine, St. Louis, MO, United States., Beaudoin FL; Department of Epidemiology, Brown University, Providence, RI, United States., An X; Department of Anesthesiology, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Stevens JS; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, United States., Neylan TC; Departments of Psychiatry and Neurology, University of California San Francisco, San Francisco, CA, United States., Jovanovic T; Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI, United States., Germine LT; Institute for Technology in Psychiatry, McLean Hospital, Belmont, MA, United States.; The Many Brains Project, Belmont, MA, United States.; Department of Psychiatry, Harvard Medical School, Boston, MA, United States., Rauch SL; Institute for Technology in Psychiatry, McLean Hospital, Belmont, MA, United States.; Department of Psychiatry, Harvard Medical School, Boston, MA, United States.; Department of Psychiatry, McLean Hospital, Belmont, MA, United States., Haran JP; Department of Emergency Medicine, University of Massachusetts Chan Medical School, Worcester, MA, United States., Storrow AB; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, United States., Lewandowski C; Department of Emergency Medicine, Henry Ford Health System, Detroit, MI, United States., Hendry PL; Department of Emergency Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, FL, United States., Sheikh S; Department of Emergency Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, FL, United States., Jones CW; Department of Emergency Medicine, Cooper Medical School of Rowan University, Camden, NJ, United States., Punches BE; Department of Emergency Medicine, Ohio State University College of Medicine, Columbus, OH, United States.; College of Nursing, Ohio State University, Columbus, OH, United States., Hudak LA; Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, United States., Pascual JL; Departments of Surgery and Neurosurgery, University of Pennsylvania, Philadelphia, PA, United States.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Seamon MJ; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.; Division of Traumatology, Surgical Critical Care and Emergency Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA, United States., Pearson C; Department of Emergency Medicine, Wayne State University, Ascension St. John Hospital, Detroit, MI, United States., Peak DA; Department of Emergency  Medicine, Massachusetts General Hospital, Boston, MA, United States.; Department of Emergency Medicine, Harvard Medical School, Boston, MA, United States., Merchant RC; Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, United States., Domeier RM; Department of Emergency Medicine, Trinity Health-Ann Arbor, Ypsilanti, MI, United States., Rathlev NK; Department of Emergency Medicine, University of Massachusetts Medical School-Baystate, Springfield, MA, United States., O'Neil BJ; Department of Emergency Medicine, Wayne State University, Detroit Receiving Hospital, Detroit, MI, United States., Sanchez LD; Department of Emergency Medicine, Harvard Medical School, Boston, MA, United States.; Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, United States., Bruce SE; Department of Psychological Sciences, University of Missouri-St. Louis, St. Louis, MO, United States., Sheridan JF; Division of Biosciences, Ohio State University College of Dentistry, Columbus, OH, United States.; Institute for Behavioral Medicine Research, OSU Wexner Medical Center, Columbus, OH, United States., Kessler RC; Department of Health Care Policy, Harvard Medical School, Boston, MA, United States., Koenen KC; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, United States., Ressler KJ; Department of Psychiatry, Harvard Medical School, Boston, MA, United States.; Division of Depression and Anxiety, McLean Hospital, Belmont, MA, United States., Linnstaedt SD; Department of Anesthesiology, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Source: Pain [Pain] 2025 Jun 18; Vol. 166 (9), pp. 2103-2115. Date of Electronic Publication: 2025 Jun 18.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7508686 Publication Model: Electronic Cited Medium: Internet ISSN: 1872-6623 (Electronic) Linking ISSN: 03043959 NLM ISO Abbreviation: Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Early life adversity increases risk for chronic post-traumatic pain, data from humans and rodents.
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