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Poor efficacy of anti PD-1 antibody based immunotherapy in patients with acral melanoma: results from the Spanish Melanoma Group (GEM) registry.

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Title: Poor efficacy of anti PD-1 antibody based immunotherapy in patients with acral melanoma: results from the Spanish Melanoma Group (GEM) registry.
Authors: Gonzalez-Cao M; Medical Oncology Department, Instituto Oncologico Dr Rosell, Dexeus University Hospital, Carrer de Sabino Arana, 5, Les Corts, 08028, Barcelona, Spain. mgonzalezcao@oncorosell.com., Berciano-Guerrero MÁ; Medical Oncology Department, Hospital Regional Universitario de Málaga (HRU), Instituto de Investigaciones Biomédicas de Málaga (IBIMA), Málaga, Spain., Muñoz-Couselo E; Medical Oncology Department. Hospital, Institute of Oncology (VHIO), Universitari Vall d Hebron y Vall d Hebron, Barcelona, Spain., Manzano JL; Medical Oncology Department, Instituto Catalán de Oncología, ICO-Badalona, H. Germans Triasi Pujol, Badalona, Spain., Cerezuela-Fuentes P; Medical Oncology Department, Hospital Clínico Universitario Virgen de La Arrixaca, Instituto Murciano de Investigación Biosanitaria (IMIB)-Arrixaca, Ciudad de Murcia, Spain., Crespo G; Medical Oncology Department, Hospital Universitario de Burgos, Burgos, Spain., Soria A; Medical Oncology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain., de Miguel PA; Medical Oncology Department, Hospital Universitario San Pedro de Alcántara, Cáceres, Spain., Gutiérrez Sanz L; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain., de la Rosa CA; Medical Oncology Department, Hospital Universitario Clínico San Carlos, Madrid, Spain., García Castaño A; Medical Oncology Department, Hospital Universitario Marqués de Valdecilla, Santander, Spain., Puértolas T; Medical Oncology Department, Hospital Universitario Miguel Servet, Saragossa, Spain., Espinosa E; Medical Oncology Department, Hospital Universitario La Paz, CIBERONC, Madrid, Spain., Medina J; Medical Oncology Department, Hospital Universitario Toledo, Toledo, Spain., Bellido L; Medical Oncology Department, Complejo Asistencial Universitario de Salamanca, Salamanca, Spain., Berrocal A; Medical Oncology Department, Hospital General Universitario Valencia, Valencia, Spain., Majem M; Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., López Castro R; Medical Oncology Department, Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Fernandez LA; Medical Oncology Department, Parc Tauli Hospital Universitari, Barcelona, Spain., Garcia F; Medical Oncology Department, Complejo Universitario Pontevedra, Pontevedra, Spain., de la Borbolla MR; Medical Oncology Department, Hospital Universitario de Valme, Sevilla, Spain., Martín Algarra S; Medical Oncology Department, Clínica Universidad de Navarra, Pamplona, Spain., Márquez-Rodas I; Medical Oncology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Source: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2026 Feb; Vol. 28 (2), pp. 645-653. Date of Electronic Publication: 2025 Aug 21.
Publication Type: Journal Article
Journal Info: Publisher: Springer Italia Country of Publication: Italy NLM ID: 101247119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-3055 (Electronic) Linking ISSN: 1699048X NLM ISO Abbreviation: Clin Transl Oncol Subsets: MEDLINE
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  Data: Poor efficacy of anti PD-1 antibody based immunotherapy in patients with acral melanoma: results from the Spanish Melanoma Group (GEM) registry.
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  Data: <searchLink fieldCode="AU" term="%22Gonzalez-Cao+M%22">Gonzalez-Cao M</searchLink>; Medical Oncology Department, Instituto Oncologico Dr Rosell, Dexeus University Hospital, Carrer de Sabino Arana, 5, Les Corts, 08028, Barcelona, Spain. mgonzalezcao@oncorosell.com.<br /><searchLink fieldCode="AU" term="%22Berciano-Guerrero+MÁ%22">Berciano-Guerrero MÁ</searchLink>; Medical Oncology Department, Hospital Regional Universitario de Málaga (HRU), Instituto de Investigaciones Biomédicas de Málaga (IBIMA), Málaga, Spain.<br /><searchLink fieldCode="AU" term="%22Muñoz-Couselo+E%22">Muñoz-Couselo E</searchLink>; Medical Oncology Department. Hospital, Institute of Oncology (VHIO), Universitari Vall d Hebron y Vall d Hebron, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Manzano+JL%22">Manzano JL</searchLink>; Medical Oncology Department, Instituto Catalán de Oncología, ICO-Badalona, H. Germans Triasi Pujol, Badalona, Spain.<br /><searchLink fieldCode="AU" term="%22Cerezuela-Fuentes+P%22">Cerezuela-Fuentes P</searchLink>; Medical Oncology Department, Hospital Clínico Universitario Virgen de La Arrixaca, Instituto Murciano de Investigación Biosanitaria (IMIB)-Arrixaca, Ciudad de Murcia, Spain.<br /><searchLink fieldCode="AU" term="%22Crespo+G%22">Crespo G</searchLink>; Medical Oncology Department, Hospital Universitario de Burgos, Burgos, Spain.<br /><searchLink fieldCode="AU" term="%22Soria+A%22">Soria A</searchLink>; Medical Oncology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22de+Miguel+PA%22">de Miguel PA</searchLink>; Medical Oncology Department, Hospital Universitario San Pedro de Alcántara, Cáceres, Spain.<br /><searchLink fieldCode="AU" term="%22Gutiérrez+Sanz+L%22">Gutiérrez Sanz L</searchLink>; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22de+la+Rosa+CA%22">de la Rosa CA</searchLink>; Medical Oncology Department, Hospital Universitario Clínico San Carlos, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22García+Castaño+A%22">García Castaño A</searchLink>; Medical Oncology Department, Hospital Universitario Marqués de Valdecilla, Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Puértolas+T%22">Puértolas T</searchLink>; Medical Oncology Department, Hospital Universitario Miguel Servet, Saragossa, Spain.<br /><searchLink fieldCode="AU" term="%22Espinosa+E%22">Espinosa E</searchLink>; Medical Oncology Department, Hospital Universitario La Paz, CIBERONC, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Medina+J%22">Medina J</searchLink>; Medical Oncology Department, Hospital Universitario Toledo, Toledo, Spain.<br /><searchLink fieldCode="AU" term="%22Bellido+L%22">Bellido L</searchLink>; Medical Oncology Department, Complejo Asistencial Universitario de Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Berrocal+A%22">Berrocal A</searchLink>; Medical Oncology Department, Hospital General Universitario Valencia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Majem+M%22">Majem M</searchLink>; Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22López+Castro+R%22">López Castro R</searchLink>; Medical Oncology Department, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Fernandez+LA%22">Fernandez LA</searchLink>; Medical Oncology Department, Parc Tauli Hospital Universitari, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Garcia+F%22">Garcia F</searchLink>; Medical Oncology Department, Complejo Universitario Pontevedra, Pontevedra, Spain.<br /><searchLink fieldCode="AU" term="%22de+la+Borbolla+MR%22">de la Borbolla MR</searchLink>; Medical Oncology Department, Hospital Universitario de Valme, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Martín+Algarra+S%22">Martín Algarra S</searchLink>; Medical Oncology Department, Clínica Universidad de Navarra, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Márquez-Rodas+I%22">Márquez-Rodas I</searchLink>; Medical Oncology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
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