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Efficacy and safety of 3CL protease inhibitors in patients with mild or moderate COVID-19: a systematic review and meta-analysis of randomized controlled trials.

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Title: Efficacy and safety of 3CL protease inhibitors in patients with mild or moderate COVID-19: a systematic review and meta-analysis of randomized controlled trials.
Authors: Lee NJ; Faculty of Medicine, Federal University of São Paulo, R. Botucatu, 740, São Paulo, Brazil. nicole.lee@unifesp.br., Katsuyama ES; Department of Medicine, FMABC University Centre, São Paulo, Brazil., Fukunaga CK; Department of Medicine, FMABC University Centre, São Paulo, Brazil., Neto WF; Faculty of Medicine, UNIFIPA University Centre, Sao Paulo, Brazil., Coan ACC; Faculty of Medicine, Federal University of Espirito Santo, Vitoria, Espirito Santo, Brazil., Faria HS; Faculty of Medicine, Federal University of Santa Maria, Santa Maria, Rio Grande do Sul, Brazil., Medeiros EA; Department of Infectious Diseases, Federal University of São Paulo (UNIFESP), Sao Paulo, Brazil.
Source: Virology journal [Virol J] 2025 Aug 21; Vol. 22 (1), pp. 286. Date of Electronic Publication: 2025 Aug 21.
Publication Type: Journal Article; Systematic Review; Meta-Analysis; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101231645 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-422X (Electronic) Linking ISSN: 1743422X NLM ISO Abbreviation: Virol J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and safety of 3CL protease inhibitors in patients with mild or moderate COVID-19: a systematic review and meta-analysis of randomized controlled trials.
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  Data: <searchLink fieldCode="AU" term="%22Lee+NJ%22">Lee NJ</searchLink>; Faculty of Medicine, Federal University of São Paulo, R. Botucatu, 740, São Paulo, Brazil. nicole.lee@unifesp.br.<br /><searchLink fieldCode="AU" term="%22Katsuyama+ES%22">Katsuyama ES</searchLink>; Department of Medicine, FMABC University Centre, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Fukunaga+CK%22">Fukunaga CK</searchLink>; Department of Medicine, FMABC University Centre, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Neto+WF%22">Neto WF</searchLink>; Faculty of Medicine, UNIFIPA University Centre, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Coan+ACC%22">Coan ACC</searchLink>; Faculty of Medicine, Federal University of Espirito Santo, Vitoria, Espirito Santo, Brazil.<br /><searchLink fieldCode="AU" term="%22Faria+HS%22">Faria HS</searchLink>; Faculty of Medicine, Federal University of Santa Maria, Santa Maria, Rio Grande do Sul, Brazil.<br /><searchLink fieldCode="AU" term="%22Medeiros+EA%22">Medeiros EA</searchLink>; Department of Infectious Diseases, Federal University of São Paulo (UNIFESP), Sao Paulo, Brazil.
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  Data: <searchLink fieldCode="JN" term="%22101231645%22">Virology journal</searchLink> [Virol J] 2025 Aug 21; Vol. 22 (1), pp. 286. <i>Date of Electronic Publication: </i>2025 Aug 21.
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