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Targeting cancer metabolism: Therapeutic potential of the fatty acid synthase (FASN) inhibitors.

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Title: Targeting cancer metabolism: Therapeutic potential of the fatty acid synthase (FASN) inhibitors.
Authors: Nuzzo PV; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA., Rodrigues S; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA., Ribeiro CF; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA., Teixeira IF; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA., Fanelli GN; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy., Bleve S; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Ravera F; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy., Pakula H; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA., Pederzoli F; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA., Nanus DM; Department of Medicine, Weill Cornell Medicine, New York, NY, USA; Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Department of Urology, Weill Cornell Medicine, New York, NY, USA., Loda M; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA; The Broad Institute of Harvard and MIT, Cambridge, MA, USA; The New York Genome Center, New York, NY, USA; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. Electronic address: mloda@med.cornell.edu.
Source: Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2025 Oct; Vol. 214, pp. 104910. Date of Electronic Publication: 2025 Aug 20.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Netherlands NLM ID: 8916049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0461 (Electronic) Linking ISSN: 10408428 NLM ISO Abbreviation: Crit Rev Oncol Hematol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting cancer metabolism: Therapeutic potential of the fatty acid synthase (FASN) inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Nuzzo+PV%22">Nuzzo PV</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Rodrigues+S%22">Rodrigues S</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ribeiro+CF%22">Ribeiro CF</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Teixeira+IF%22">Teixeira IF</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Fanelli+GN%22">Fanelli GN</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Bleve+S%22">Bleve S</searchLink>; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy.<br /><searchLink fieldCode="AU" term="%22Ravera+F%22">Ravera F</searchLink>; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Pakula+H%22">Pakula H</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pederzoli+F%22">Pederzoli F</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Nanus+DM%22">Nanus DM</searchLink>; Department of Medicine, Weill Cornell Medicine, New York, NY, USA; Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Department of Urology, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Loda+M%22">Loda M</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA; The Broad Institute of Harvard and MIT, Cambridge, MA, USA; The New York Genome Center, New York, NY, USA; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. Electronic address: mloda@med.cornell.edu.
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  Data: <searchLink fieldCode="JN" term="%228916049%22">Critical reviews in oncology/hematology</searchLink> [Crit Rev Oncol Hematol] 2025 Oct; Vol. 214, pp. 104910. <i>Date of Electronic Publication: </i>2025 Aug 20.
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