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Red light photodynamic therapy with 10% aminolevulinic acid gel showed efficacy for treatment of superficial basal cell carcinoma in a randomized, vehicle controlled, double-blind, multicenter phase III study.

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Title: Red light photodynamic therapy with 10% aminolevulinic acid gel showed efficacy for treatment of superficial basal cell carcinoma in a randomized, vehicle controlled, double-blind, multicenter phase III study.
Authors: Schlesinger T; Clinical Research Center of the Carolinas, Charleston, South Carolina., Chapman MS; Dept. Of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire., Tu JH; Skin Search of Rochester, Rochester, New York., Cohen JL; AboutSkin Dermatology & Derm Surgery, Greenwood Village, Colorado., Strasswimmer J; Dermatology Associates PA of the Palm Beaches, Delray Location, Delray Beach, Florida., Zeitouni NC; Medical Dermatology Specialists, Phoenix, Arizona., Torres A; UF Department of Dermatology, University of Florida, Gainesville, Florida., Jazayeri SS; Alliance Dermatology & Mohs Center, Phoenix, Arizona., Goldman MP; Cosmetic Laser and Dermatology: A Platinum Dermatology Company, San Diego, California., Ibrahim SF; Rochester Dermatologic Surgery, Victor, New York., Lain EL; Austin Institute for Clinical Research, Inc, Pflugerville, Texas., Couvillion MP; Austin Institute for Clinical Research, Inc, Houston, Texas., Bruce S; Austin Institute for Clinical Research, Inc, Houston, Texas., Laquer VT; First OC Dermatology Research, Fountain Valley, California., Hanke CW; Laser & Skin Surgery Center of Indiana (The Lassi), Indianapolis, Indiana., Ozog DM; Department of Dermatology, Henry Ford Health, Detroit, Michigan; Department of Medicine, Michigan State University, East Lansing, Michigan., Schneider J; The Narrows Institute for Biomedical Research and Education, Inc., Brooklyn, New York., Markowitz O; The Narrows Institute for Biomedical Research and Education, Inc., Brooklyn, New York., Berman B; Center for Clinical and Cosmetic Research, Aventura, Florida., Nestor MS; Center for Clinical and Cosmetic Research, Aventura, Florida., Gold MH; Tennessee Clinical Research Center, Nashville, Tennessee., Munavalli GS; Dermatology, Laser & Vein Specialists of the Carolinas, Charlotte, North Carolina., Forsha DW; Jordan Valley Dermatology Center, West Jordan, Utah., Siegel DM; Veterans Affairs New York Harbor Healthcare System-Brooklyn, Brooklyn, New York., Mrohs D; Biofrontera Discovery GmbH, Leverkusen, Germany., Schmitz B; Biofrontera Discovery GmbH, Leverkusen, Germany., Schäning R; Biofrontera Discovery GmbH, Leverkusen, Germany., Pospiech N; Biofrontera Bioscience GmbH, Leverkusen, Germany., Lyons J; Biofrontera Inc., Woburn, Massachusetts., Foguet M; Biofrontera Bioscience GmbH, Leverkusen, Germany., Lübbert M; Biofrontera Discovery GmbH, Leverkusen, Germany. Electronic address: m.luebbert@bfinc.com., Lübbert H; Biofrontera Discovery GmbH, Leverkusen, Germany; Biofrontera Inc., Woburn, Massachusetts., Pariser DM; Eastern Virginia Medical School and Virginia Clinical Research, Inc., Norfolk, Virginia.
Source: Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2025 Dec; Vol. 93 (6), pp. 1489-1498. Date of Electronic Publication: 2025 Aug 20.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 7907132 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6787 (Electronic) Linking ISSN: 01909622 NLM ISO Abbreviation: J Am Acad Dermatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Red light photodynamic therapy with 10% aminolevulinic acid gel showed efficacy for treatment of superficial basal cell carcinoma in a randomized, vehicle controlled, double-blind, multicenter phase III study.
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  Data: <searchLink fieldCode="AU" term="%22Schlesinger+T%22">Schlesinger T</searchLink>; Clinical Research Center of the Carolinas, Charleston, South Carolina.<br /><searchLink fieldCode="AU" term="%22Chapman+MS%22">Chapman MS</searchLink>; Dept. Of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.<br /><searchLink fieldCode="AU" term="%22Tu+JH%22">Tu JH</searchLink>; Skin Search of Rochester, Rochester, New York.<br /><searchLink fieldCode="AU" term="%22Cohen+JL%22">Cohen JL</searchLink>; AboutSkin Dermatology & Derm Surgery, Greenwood Village, Colorado.<br /><searchLink fieldCode="AU" term="%22Strasswimmer+J%22">Strasswimmer J</searchLink>; Dermatology Associates PA of the Palm Beaches, Delray Location, Delray Beach, Florida.<br /><searchLink fieldCode="AU" term="%22Zeitouni+NC%22">Zeitouni NC</searchLink>; Medical Dermatology Specialists, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Torres+A%22">Torres A</searchLink>; UF Department of Dermatology, University of Florida, Gainesville, Florida.<br /><searchLink fieldCode="AU" term="%22Jazayeri+SS%22">Jazayeri SS</searchLink>; Alliance Dermatology & Mohs Center, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Goldman+MP%22">Goldman MP</searchLink>; Cosmetic Laser and Dermatology: A Platinum Dermatology Company, San Diego, California.<br /><searchLink fieldCode="AU" term="%22Ibrahim+SF%22">Ibrahim SF</searchLink>; Rochester Dermatologic Surgery, Victor, New York.<br /><searchLink fieldCode="AU" term="%22Lain+EL%22">Lain EL</searchLink>; Austin Institute for Clinical Research, Inc, Pflugerville, Texas.<br /><searchLink fieldCode="AU" term="%22Couvillion+MP%22">Couvillion MP</searchLink>; Austin Institute for Clinical Research, Inc, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Bruce+S%22">Bruce S</searchLink>; Austin Institute for Clinical Research, Inc, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Laquer+VT%22">Laquer VT</searchLink>; First OC Dermatology Research, Fountain Valley, California.<br /><searchLink fieldCode="AU" term="%22Hanke+CW%22">Hanke CW</searchLink>; Laser & Skin Surgery Center of Indiana (The Lassi), Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Ozog+DM%22">Ozog DM</searchLink>; Department of Dermatology, Henry Ford Health, Detroit, Michigan; Department of Medicine, Michigan State University, East Lansing, Michigan.<br /><searchLink fieldCode="AU" term="%22Schneider+J%22">Schneider J</searchLink>; The Narrows Institute for Biomedical Research and Education, Inc., Brooklyn, New York.<br /><searchLink fieldCode="AU" term="%22Markowitz+O%22">Markowitz O</searchLink>; The Narrows Institute for Biomedical Research and Education, Inc., Brooklyn, New York.<br /><searchLink fieldCode="AU" term="%22Berman+B%22">Berman B</searchLink>; Center for Clinical and Cosmetic Research, Aventura, Florida.<br /><searchLink fieldCode="AU" term="%22Nestor+MS%22">Nestor MS</searchLink>; Center for Clinical and Cosmetic Research, Aventura, Florida.<br /><searchLink fieldCode="AU" term="%22Gold+MH%22">Gold MH</searchLink>; Tennessee Clinical Research Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Munavalli+GS%22">Munavalli GS</searchLink>; Dermatology, Laser & Vein Specialists of the Carolinas, Charlotte, North Carolina.<br /><searchLink fieldCode="AU" term="%22Forsha+DW%22">Forsha DW</searchLink>; Jordan Valley Dermatology Center, West Jordan, Utah.<br /><searchLink fieldCode="AU" term="%22Siegel+DM%22">Siegel DM</searchLink>; Veterans Affairs New York Harbor Healthcare System-Brooklyn, Brooklyn, New York.<br /><searchLink fieldCode="AU" term="%22Mrohs+D%22">Mrohs D</searchLink>; Biofrontera Discovery GmbH, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Schmitz+B%22">Schmitz B</searchLink>; Biofrontera Discovery GmbH, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Schäning+R%22">Schäning R</searchLink>; Biofrontera Discovery GmbH, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Pospiech+N%22">Pospiech N</searchLink>; Biofrontera Bioscience GmbH, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Lyons+J%22">Lyons J</searchLink>; Biofrontera Inc., Woburn, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Foguet+M%22">Foguet M</searchLink>; Biofrontera Bioscience GmbH, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Lübbert+M%22">Lübbert M</searchLink>; Biofrontera Discovery GmbH, Leverkusen, Germany. Electronic address: m.luebbert@bfinc.com.<br /><searchLink fieldCode="AU" term="%22Lübbert+H%22">Lübbert H</searchLink>; Biofrontera Discovery GmbH, Leverkusen, Germany; Biofrontera Inc., Woburn, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Pariser+DM%22">Pariser DM</searchLink>; Eastern Virginia Medical School and Virginia Clinical Research, Inc., Norfolk, Virginia.
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  Data: <searchLink fieldCode="JN" term="%227907132%22">Journal of the American Academy of Dermatology</searchLink> [J Am Acad Dermatol] 2025 Dec; Vol. 93 (6), pp. 1489-1498. <i>Date of Electronic Publication: </i>2025 Aug 20.
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  Data: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7907132 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6787 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201909622%22">01909622 </searchLink><i>NLM ISO Abbreviation: </i>J Am Acad Dermatol <i>Subsets: </i>MEDLINE
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