Hemoglobin as a pseudoperoxidase and drug target for oxidative stress-related diseases.

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Title: Hemoglobin as a pseudoperoxidase and drug target for oxidative stress-related diseases.
Authors: Won W; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea., Lee EH; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea., Gotina L; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea., Chun H; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.; College of Pharmacy, Yonsei-SL Bigen Research Institute, Yonsei University, Incheon, Korea., Lee JH; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea., Bhalla M; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.; IBS School, University of Science and Technology (UST), Daejeon, South Korea., Park U; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea., Kim D; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea., Kim TY; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea., Choi JW; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea., Kim Y; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea., Park SJ; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea., Lim J; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.; IBS School, University of Science and Technology (UST), Daejeon, South Korea., Park JH; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea., Kim HJ; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea., Heo JY; Department of Biochemistry, Chungnam National University College of Medicine, Daejeon, Republic of Korea.; System Network Inflammation Control Research Center, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Chung W; Department of Anesthesiology and Pain Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Republic of Korea., Oh MJ; Graduate School of Analytical Science & Technology, Chungnam National University, Daejeon, Republic of Korea., An HJ; Graduate School of Analytical Science & Technology, Chungnam National University, Daejeon, Republic of Korea., Lee J; VA Boston Healthcare System, U.S. Department of Veteran Affairs, Boston, MA, USA.; Boston University Alzheimer's Disease Research Center and Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Oh SJ; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea., Ryu H; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea., Pae AN; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea., Park KD; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea. kdpark@kist.re.kr.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea. kdpark@kist.re.kr., Lee CJ; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea. cjl@ibs.re.kr.; IBS School, University of Science and Technology (UST), Daejeon, South Korea. cjl@ibs.re.kr.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2025 Aug 22; Vol. 10 (1), pp. 270. Date of Electronic Publication: 2025 Aug 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2059-3635
DOI:10.1038/s41392-025-02366-w