Hemoglobin as a pseudoperoxidase and drug target for oxidative stress-related diseases.

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Title: Hemoglobin as a pseudoperoxidase and drug target for oxidative stress-related diseases.
Authors: Won W; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea., Lee EH; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea., Gotina L; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea., Chun H; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.; College of Pharmacy, Yonsei-SL Bigen Research Institute, Yonsei University, Incheon, Korea., Lee JH; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea., Bhalla M; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.; IBS School, University of Science and Technology (UST), Daejeon, South Korea., Park U; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea., Kim D; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea., Kim TY; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea., Choi JW; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea., Kim Y; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea., Park SJ; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea., Lim J; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.; IBS School, University of Science and Technology (UST), Daejeon, South Korea., Park JH; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea., Kim HJ; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea., Heo JY; Department of Biochemistry, Chungnam National University College of Medicine, Daejeon, Republic of Korea.; System Network Inflammation Control Research Center, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Chung W; Department of Anesthesiology and Pain Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Republic of Korea., Oh MJ; Graduate School of Analytical Science & Technology, Chungnam National University, Daejeon, Republic of Korea., An HJ; Graduate School of Analytical Science & Technology, Chungnam National University, Daejeon, Republic of Korea., Lee J; VA Boston Healthcare System, U.S. Department of Veteran Affairs, Boston, MA, USA.; Boston University Alzheimer's Disease Research Center and Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Oh SJ; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea., Ryu H; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea., Pae AN; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea., Park KD; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea. kdpark@kist.re.kr.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea. kdpark@kist.re.kr., Lee CJ; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea. cjl@ibs.re.kr.; IBS School, University of Science and Technology (UST), Daejeon, South Korea. cjl@ibs.re.kr.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2025 Aug 22; Vol. 10 (1), pp. 270. Date of Electronic Publication: 2025 Aug 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
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  Data: Hemoglobin as a pseudoperoxidase and drug target for oxidative stress-related diseases.
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  Data: <searchLink fieldCode="AU" term="%22Won+W%22">Won W</searchLink>; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+EH%22">Lee EH</searchLink>; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Gotina+L%22">Gotina L</searchLink>; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chun+H%22">Chun H</searchLink>; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.; College of Pharmacy, Yonsei-SL Bigen Research Institute, Yonsei University, Incheon, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JH%22">Lee JH</searchLink>; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bhalla+M%22">Bhalla M</searchLink>; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.; IBS School, University of Science and Technology (UST), Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+U%22">Park U</searchLink>; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+D%22">Kim D</searchLink>; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+TY%22">Kim TY</searchLink>; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+JW%22">Choi JW</searchLink>; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+Y%22">Kim Y</searchLink>; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+SJ%22">Park SJ</searchLink>; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+J%22">Lim J</searchLink>; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.; IBS School, University of Science and Technology (UST), Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+JH%22">Park JH</searchLink>; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HJ%22">Kim HJ</searchLink>; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Heo+JY%22">Heo JY</searchLink>; Department of Biochemistry, Chungnam National University College of Medicine, Daejeon, Republic of Korea.; System Network Inflammation Control Research Center, Chungnam National University College of Medicine, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chung+W%22">Chung W</searchLink>; Department of Anesthesiology and Pain Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Oh+MJ%22">Oh MJ</searchLink>; Graduate School of Analytical Science & Technology, Chungnam National University, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22An+HJ%22">An HJ</searchLink>; Graduate School of Analytical Science & Technology, Chungnam National University, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; VA Boston Healthcare System, U.S. Department of Veteran Affairs, Boston, MA, USA.; Boston University Alzheimer's Disease Research Center and Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Oh+SJ%22">Oh SJ</searchLink>; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ryu+H%22">Ryu H</searchLink>; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Pae+AN%22">Pae AN</searchLink>; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+KD%22">Park KD</searchLink>; Center for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea. kdpark@kist.re.kr.; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea. kdpark@kist.re.kr.<br /><searchLink fieldCode="AU" term="%22Lee+CJ%22">Lee CJ</searchLink>; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea. cjl@ibs.re.kr.; IBS School, University of Science and Technology (UST), Daejeon, South Korea. cjl@ibs.re.kr.
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