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SARS-CoV-2 infection induces pro-fibrotic and pro-thrombotic foam cell formation.

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Title: SARS-CoV-2 infection induces pro-fibrotic and pro-thrombotic foam cell formation.
Authors: Battaglia DM; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA.; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Post CE; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Yao W; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Jilin University, The First Hospital, 130021, Changchun, China., Wahl A; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA. awahl@uab.edu.; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. awahl@uab.edu.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. awahl@uab.edu.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. awahl@uab.edu., Gralinski LE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Liu H; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Dang H; Marsico Lung Institute, University of North Carolina at Chapel, Chapel Hill, NC, USA., Madden VJ; Microscopy Services Laboratory, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., White KK; Microscopy Services Laboratory, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Leist SR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Dinnion KH 3rd; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., De la Cruz G; Pathology Services Core, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Midkiff BR; Pathology Services Core, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Froggatt HM; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gully K; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Zweigart M; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Reader JR; California National Primate Research Center, University of California Davis, Davis, CA, USA., Olstad KJ; California National Primate Research Center, University of California Davis, Davis, CA, USA., Everitt JI; Department of Pathology, Duke University, Durham, NC, USA., Van Rompay KKA; California National Primate Research Center, University of California Davis, Davis, CA, USA., De Paris K; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sajti E; Department of Pediatrics, University of California San Diego, San Diego, CA, USA., Pickles RJ; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Marsico Lung Institute, University of North Carolina at Chapel, Chapel Hill, NC, USA., Browne EP; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Jones CD; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Boucher RC Jr; Marsico Lung Institute, University of North Carolina at Chapel, Chapel Hill, NC, USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Rapidly Emerging Antiviral Drug Discovery Initiative, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Garcia JV; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA. jvgarcia@uab.edu.; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. jvgarcia@uab.edu.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. jvgarcia@uab.edu.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. jvgarcia@uab.edu.
Source: Nature microbiology [Nat Microbiol] 2025 Oct; Vol. 10 (10), pp. 2616-2630. Date of Electronic Publication: 2025 Aug 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101674869 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2058-5276 (Electronic) Linking ISSN: 20585276 NLM ISO Abbreviation: Nat Microbiol Subsets: MEDLINE
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  Data: SARS-CoV-2 infection induces pro-fibrotic and pro-thrombotic foam cell formation.
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  Data: <searchLink fieldCode="AU" term="%22Battaglia+DM%22">Battaglia DM</searchLink>; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA.; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Post+CE%22">Post CE</searchLink>; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Yao+W%22">Yao W</searchLink>; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Jilin University, The First Hospital, 130021, Changchun, China.<br /><searchLink fieldCode="AU" term="%22Wahl+A%22">Wahl A</searchLink>; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA. awahl@uab.edu.; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. awahl@uab.edu.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. awahl@uab.edu.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. awahl@uab.edu.<br /><searchLink fieldCode="AU" term="%22Gralinski+LE%22">Gralinski LE</searchLink>; 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Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Reader+JR%22">Reader JR</searchLink>; California National Primate Research Center, University of California Davis, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Olstad+KJ%22">Olstad KJ</searchLink>; California National Primate Research Center, University of California Davis, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Everitt+JI%22">Everitt JI</searchLink>; Department of Pathology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Van+Rompay+KKA%22">Van Rompay KKA</searchLink>; California National Primate Research Center, University of California Davis, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22De+Paris+K%22">De Paris K</searchLink>; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Sajti+E%22">Sajti E</searchLink>; Department of Pediatrics, University of California San Diego, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pickles+RJ%22">Pickles RJ</searchLink>; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Marsico Lung Institute, University of North Carolina at Chapel, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Browne+EP%22">Browne EP</searchLink>; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Jones+CD%22">Jones CD</searchLink>; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Boucher+RC+Jr%22">Boucher RC Jr</searchLink>; Marsico Lung Institute, University of North Carolina at Chapel, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Baric+RS%22">Baric RS</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Rapidly Emerging Antiviral Drug Discovery Initiative, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Garcia+JV%22">Garcia JV</searchLink>; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA. jvgarcia@uab.edu.; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. jvgarcia@uab.edu.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. jvgarcia@uab.edu.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. jvgarcia@uab.edu.
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