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Refining prognostic stratification in salvage radiotherapy for prostate cancer: a retrospective multicenter cohort study using PSMA-PET and machine learning.

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Title: Refining prognostic stratification in salvage radiotherapy for prostate cancer: a retrospective multicenter cohort study using PSMA-PET and machine learning.
Authors: Medici F; Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif 94805, France; Radiation Oncology Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum - Bologna University, Bologna, Italy. Electronic address: federica.medici@gustaveroussy.fr., Aebersold DM; Department of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. Electronic address: daniel.aebersold@insel.ch., Casuscelli J; Department of Urology, University Hospital, LMU Munich, Munich, Germany. Electronic address: jozefina.casuscelli@med.uni-muenchen.de., Emmett L; Department of Theranostics and Nuclear Medicine, St. Vincent's Hospital, Sydney, Australia; St. Vincent's Clinical School, University of New South Wales, Sydney, Australia. Electronic address: l.emmett@unsw.edu.au., Fanti S; Nuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. Electronic address: s.fanti@unibo.it., Farolfi A; Nuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. Electronic address: andrea.farolfi6@unibo.it., Guckenberger M; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Zurich, Switzerland. Electronic address: matthias.guckenberger@usz.ch., Hruby G; Department of Radiation Oncology, Royal North Shore Hospital, University of Sydney, Sydney, Australia. Electronic address: george.hruby@sydney.edu.au., Koerber SA; Department of Radiation Oncology, Barmherzige Brüder Hospital Regensburg, Regensburg, Germany; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany. Electronic address: Stefan.Koerber@med.uni-heidelberg.de., Thoma SA; Department of Radiation Oncology, Kantonsspital Aarau, Aarau, Switzerland. Electronic address: Stephanie.Kroeze@usz.ch., Peeken JC; Deutsches Konsortium für Translationale Krebsforschung (DKTK), Partner Site Munich, Munich, Germany; Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich (TUM), Munich, Germany. Electronic address: jan.peeken@tum.de., Rogowski P; Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistr. 15, 81377 Munich, Germany. Electronic address: Paul.Rogowski@med.uni-muenchen.de., Scharl S; Department of Radiation Oncology, University of Ulm, Ulm, Germany. Electronic address: sophia.scharl@uniklinik-ulm.de., Shelan M; Department of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. Electronic address: mohamed.shelan@insel.ch., Spohn SKB; Department of Radiation Oncology, Medical Center, University of Freiburg, Freiburg, Germany; Deutsches Konsortium für Translationale Krebsforschung (DKTK), Partner Site Freiburg, Freiburg, Germany; Berta-Ottenstein-Programm, Medical Faculty, University of Freiburg, Freiburg, Germany. Electronic address: Simon.Spohn@uniklinik-freiburg.de., Strouthos I; Department of Radiation Oncology, German Oncology Center, European University Cyprus, Limassol, Cyprus. Electronic address: Iosif.Strouthos@goc.com.cy., Vogel M; Deutsches Konsortium für Translationale Krebsforschung (DKTK), Partner Site Munich, Munich, Germany; Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich (TUM), Munich, Germany. Electronic address: marco.vogel@tum.de., Wiegel T; Department of Radiation Oncology, University of Ulm, Ulm, Germany. Electronic address: thomas.wiegel@uniklinik-ulm.de., Zamboglou C; Deutsches Konsortium für Translationale Krebsforschung (DKTK), Partner Site Munich, Munich, Germany; Department of Radiation Oncology, Medical Center, University of Freiburg, Freiburg, Germany; Department of Radiation Oncology, German Oncology Center, European University Cyprus, Limassol, Cyprus. Electronic address: constantinos.zamboglou@uniklinik-freiburg.de., Schmidt-Hegemann NS; Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistr. 15, 81377 Munich, Germany. Electronic address: Nina-Sophie.Hegemann@med.uni-muenchen.de., Morganti AG; Radiation Oncology Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum - Bologna University, Bologna, Italy; Radiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna 40138 Bologna, Italy. Electronic address: alessio.morganti2@unibo.it., Cilla S; Medical Physics Unit, Responsible Research Hospital, 86100 Campobasso, Italy. Electronic address: savino.cilla@responsible.hospital.
Source: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2025 Nov; Vol. 212, pp. 111113. Date of Electronic Publication: 2025 Aug 21.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8407192 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0887 (Electronic) Linking ISSN: 01678140 NLM ISO Abbreviation: Radiother Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Refining prognostic stratification in salvage radiotherapy for prostate cancer: a retrospective multicenter cohort study using PSMA-PET and machine learning.
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  Data: <searchLink fieldCode="AU" term="%22Medici+F%22">Medici F</searchLink>; Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif 94805, France; Radiation Oncology Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum - Bologna University, Bologna, Italy. Electronic address: federica.medici@gustaveroussy.fr.<br /><searchLink fieldCode="AU" term="%22Aebersold+DM%22">Aebersold DM</searchLink>; Department of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. Electronic address: daniel.aebersold@insel.ch.<br /><searchLink fieldCode="AU" term="%22Casuscelli+J%22">Casuscelli J</searchLink>; Department of Urology, University Hospital, LMU Munich, Munich, Germany. Electronic address: jozefina.casuscelli@med.uni-muenchen.de.<br /><searchLink fieldCode="AU" term="%22Emmett+L%22">Emmett L</searchLink>; Department of Theranostics and Nuclear Medicine, St. Vincent's Hospital, Sydney, Australia; St. Vincent's Clinical School, University of New South Wales, Sydney, Australia. Electronic address: l.emmett@unsw.edu.au.<br /><searchLink fieldCode="AU" term="%22Fanti+S%22">Fanti S</searchLink>; Nuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. Electronic address: s.fanti@unibo.it.<br /><searchLink fieldCode="AU" term="%22Farolfi+A%22">Farolfi A</searchLink>; Nuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. Electronic address: andrea.farolfi6@unibo.it.<br /><searchLink fieldCode="AU" term="%22Guckenberger+M%22">Guckenberger M</searchLink>; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Zurich, Switzerland. Electronic address: matthias.guckenberger@usz.ch.<br /><searchLink fieldCode="AU" term="%22Hruby+G%22">Hruby G</searchLink>; Department of Radiation Oncology, Royal North Shore Hospital, University of Sydney, Sydney, Australia. Electronic address: george.hruby@sydney.edu.au.<br /><searchLink fieldCode="AU" term="%22Koerber+SA%22">Koerber SA</searchLink>; Department of Radiation Oncology, Barmherzige Brüder Hospital Regensburg, Regensburg, Germany; Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany. Electronic address: Stefan.Koerber@med.uni-heidelberg.de.<br /><searchLink fieldCode="AU" term="%22Thoma+SA%22">Thoma SA</searchLink>; Department of Radiation Oncology, Kantonsspital Aarau, Aarau, Switzerland. Electronic address: Stephanie.Kroeze@usz.ch.<br /><searchLink fieldCode="AU" term="%22Peeken+JC%22">Peeken JC</searchLink>; Deutsches Konsortium für Translationale Krebsforschung (DKTK), Partner Site Munich, Munich, Germany; Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich (TUM), Munich, Germany. Electronic address: jan.peeken@tum.de.<br /><searchLink fieldCode="AU" term="%22Rogowski+P%22">Rogowski P</searchLink>; Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistr. 15, 81377 Munich, Germany. Electronic address: Paul.Rogowski@med.uni-muenchen.de.<br /><searchLink fieldCode="AU" term="%22Scharl+S%22">Scharl S</searchLink>; Department of Radiation Oncology, University of Ulm, Ulm, Germany. Electronic address: sophia.scharl@uniklinik-ulm.de.<br /><searchLink fieldCode="AU" term="%22Shelan+M%22">Shelan M</searchLink>; Department of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. Electronic address: mohamed.shelan@insel.ch.<br /><searchLink fieldCode="AU" term="%22Spohn+SKB%22">Spohn SKB</searchLink>; Department of Radiation Oncology, Medical Center, University of Freiburg, Freiburg, Germany; Deutsches Konsortium für Translationale Krebsforschung (DKTK), Partner Site Freiburg, Freiburg, Germany; Berta-Ottenstein-Programm, Medical Faculty, University of Freiburg, Freiburg, Germany. Electronic address: Simon.Spohn@uniklinik-freiburg.de.<br /><searchLink fieldCode="AU" term="%22Strouthos+I%22">Strouthos I</searchLink>; Department of Radiation Oncology, German Oncology Center, European University Cyprus, Limassol, Cyprus. Electronic address: Iosif.Strouthos@goc.com.cy.<br /><searchLink fieldCode="AU" term="%22Vogel+M%22">Vogel M</searchLink>; Deutsches Konsortium für Translationale Krebsforschung (DKTK), Partner Site Munich, Munich, Germany; Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich (TUM), Munich, Germany. Electronic address: marco.vogel@tum.de.<br /><searchLink fieldCode="AU" term="%22Wiegel+T%22">Wiegel T</searchLink>; Department of Radiation Oncology, University of Ulm, Ulm, Germany. Electronic address: thomas.wiegel@uniklinik-ulm.de.<br /><searchLink fieldCode="AU" term="%22Zamboglou+C%22">Zamboglou C</searchLink>; Deutsches Konsortium für Translationale Krebsforschung (DKTK), Partner Site Munich, Munich, Germany; Department of Radiation Oncology, Medical Center, University of Freiburg, Freiburg, Germany; Department of Radiation Oncology, German Oncology Center, European University Cyprus, Limassol, Cyprus. Electronic address: constantinos.zamboglou@uniklinik-freiburg.de.<br /><searchLink fieldCode="AU" term="%22Schmidt-Hegemann+NS%22">Schmidt-Hegemann NS</searchLink>; Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistr. 15, 81377 Munich, Germany. Electronic address: Nina-Sophie.Hegemann@med.uni-muenchen.de.<br /><searchLink fieldCode="AU" term="%22Morganti+AG%22">Morganti AG</searchLink>; Radiation Oncology Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum - Bologna University, Bologna, Italy; Radiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna 40138 Bologna, Italy. Electronic address: alessio.morganti2@unibo.it.<br /><searchLink fieldCode="AU" term="%22Cilla+S%22">Cilla S</searchLink>; Medical Physics Unit, Responsible Research Hospital, 86100 Campobasso, Italy. Electronic address: savino.cilla@responsible.hospital.
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  Data: <searchLink fieldCode="JN" term="%228407192%22">Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology</searchLink> [Radiother Oncol] 2025 Nov; Vol. 212, pp. 111113. <i>Date of Electronic Publication: </i>2025 Aug 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Scientific+Publishers%22">Elsevier Scientific Publishers </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>8407192 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0887 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201678140%22">01678140 </searchLink><i>NLM ISO Abbreviation: </i>Radiother Oncol <i>Subsets: </i>MEDLINE
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