Multi-omic identification of perineurial hyperplasia and lipid-associated nerve macrophages in human polyneuropathies.

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Title: Multi-omic identification of perineurial hyperplasia and lipid-associated nerve macrophages in human polyneuropathies.
Authors: Heming M; Department of Neurology, University Hospital Münster, Münster, Germany., Börsch AL; Department of Neurology, University Hospital Münster, Münster, Germany., Wolbert J; Department of Neurology, University Hospital Münster, Münster, Germany., Thomas C; Institute of Neuropathology, University Hospital Münster, Münster, Germany., Mausberg AK; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen, Essen, Germany., Szepanowski F; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen, Essen, Germany., Eggert B; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen, Essen, Germany., Lu IN; Department of Neurology, University Hospital Münster, Münster, Germany., Tietz J; Department of Neurology, University Hospital Münster, Münster, Germany., Dienhart F; Department of Neurology, University Hospital Münster, Münster, Germany., Meschnark M; Department of Neurology, University Hospital Münster, Münster, Germany., Strecker JK; Department of Neurology, University Hospital Schleswig-Holstein, Lübeck, Germany., Glatza M; Institute of Neuropathology, University Hospital Münster, Münster, Germany., Thomas C; Paul-Flechsig-Institute of Neuropathology, University Hospital Leipzig, Leipzig, Germany., Gmahl N; Department of Neurology, University Hospital Münster, Münster, Germany., Dambietz C; Department of Neurology, University Hospital Münster, Münster, Germany., Müther M; Department of Neurosurgery, University Hospital Münster, Münster, Germany., Uerschels AK; Department of Neurosurgery, University Hospital Essen, Essen, Germany., Keyvani K; Department of Neuropathology, University Hospital Essen, Essen, Germany., Minnerup J; Department of Neurology, University Hospital Schleswig-Holstein, Lübeck, Germany., Doppler K; Department of Neurology, University Hospital Würzburg, Würzburg, Germany., Üçeyler N; Department of Neurology, University Hospital Würzburg, Würzburg, Germany., Aprea J; DRESDEN-concept Genome Center, Center for Molecular and Cellular Bioengineering, Dresden University of Technology, Dresden, Germany., Dahl A; DRESDEN-concept Genome Center, Center for Molecular and Cellular Bioengineering, Dresden University of Technology, Dresden, Germany., Stassart R; Paul-Flechsig-Institute of Neuropathology, University Hospital Leipzig, Leipzig, Germany., Fledrich R; Institute of Anatomy, University of Leipzig, Leipzig, Germany., Wiendl H; Clinic of Neurology and Neurophysiology, University of Freiburg, Freiburg, Germany., Sommer C; Department of Neurology, University Hospital Würzburg, Würzburg, Germany., Stettner M; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen, Essen, Germany., Meyer Zu Hörste G; Department of Neurology, University Hospital Münster, Münster, Germany. gerd.meyerzuhoerste@ukmuenster.de.
Source: Nature communications [Nat Commun] 2025 Aug 23; Vol. 16 (1), pp. 7872. Date of Electronic Publication: 2025 Aug 23.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Multi-omic identification of perineurial hyperplasia and lipid-associated nerve macrophages in human polyneuropathies.
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  Data: <searchLink fieldCode="AU" term="%22Heming+M%22">Heming M</searchLink>; Department of Neurology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Börsch+AL%22">Börsch AL</searchLink>; Department of Neurology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Wolbert+J%22">Wolbert J</searchLink>; Department of Neurology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Thomas+C%22">Thomas C</searchLink>; Institute of Neuropathology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Mausberg+AK%22">Mausberg AK</searchLink>; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Szepanowski+F%22">Szepanowski F</searchLink>; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Eggert+B%22">Eggert B</searchLink>; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Lu+IN%22">Lu IN</searchLink>; Department of Neurology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Tietz+J%22">Tietz J</searchLink>; Department of Neurology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Dienhart+F%22">Dienhart F</searchLink>; Department of Neurology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Meschnark+M%22">Meschnark M</searchLink>; Department of Neurology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Strecker+JK%22">Strecker JK</searchLink>; Department of Neurology, University Hospital Schleswig-Holstein, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Glatza+M%22">Glatza M</searchLink>; Institute of Neuropathology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Thomas+C%22">Thomas C</searchLink>; Paul-Flechsig-Institute of Neuropathology, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Gmahl+N%22">Gmahl N</searchLink>; Department of Neurology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Dambietz+C%22">Dambietz C</searchLink>; Department of Neurology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Müther+M%22">Müther M</searchLink>; Department of Neurosurgery, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Uerschels+AK%22">Uerschels AK</searchLink>; Department of Neurosurgery, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Keyvani+K%22">Keyvani K</searchLink>; Department of Neuropathology, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Minnerup+J%22">Minnerup J</searchLink>; Department of Neurology, University Hospital Schleswig-Holstein, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Doppler+K%22">Doppler K</searchLink>; Department of Neurology, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Üçeyler+N%22">Üçeyler N</searchLink>; Department of Neurology, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Aprea+J%22">Aprea J</searchLink>; DRESDEN-concept Genome Center, Center for Molecular and Cellular Bioengineering, Dresden University of Technology, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Dahl+A%22">Dahl A</searchLink>; DRESDEN-concept Genome Center, Center for Molecular and Cellular Bioengineering, Dresden University of Technology, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Stassart+R%22">Stassart R</searchLink>; Paul-Flechsig-Institute of Neuropathology, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Fledrich+R%22">Fledrich R</searchLink>; Institute of Anatomy, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Wiendl+H%22">Wiendl H</searchLink>; Clinic of Neurology and Neurophysiology, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sommer+C%22">Sommer C</searchLink>; Department of Neurology, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Stettner+M%22">Stettner M</searchLink>; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Meyer+Zu+Hörste+G%22">Meyer Zu Hörste G</searchLink>; Department of Neurology, University Hospital Münster, Münster, Germany. gerd.meyerzuhoerste@ukmuenster.de.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Aug 23; Vol. 16 (1), pp. 7872. <i>Date of Electronic Publication: </i>2025 Aug 23.
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