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SARS-CoV-2 antibody responses in children exhibit higher FcR engagement and avidity than in adults.

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Title: SARS-CoV-2 antibody responses in children exhibit higher FcR engagement and avidity than in adults.
Authors: Cohen CA; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Grzelak L; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Australia., Chiu SS; Department of Paediatric and Adolescent Medicine, The University of Hong Kong and Queen Mary Hospital, Hospital Authority of Hong Kong, Hong Kong SAR, China., Hui DS; Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong SAR, China., Kwan MY; Department of Paediatric and Adolescent Medicine, Hong Kong Hospital Authority Infectious Disease Centre, Princess Margaret Hospital, Hong Kong SAR, China., Tsang OT; Infectious Diseases Centre, Princess Margaret Hospital, Hospital Authority of Hong Kong, Hong Kong SAR, China., Chan WH; Department of Paediatrics, Queen Elizabeth Hospital, Hospital Authority of Hong Kong, Hong Kong SAR, China., Yau YS; Department of Paediatrics, Queen Elizabeth Hospital, Hospital Authority of Hong Kong, Hong Kong SAR, China., Lee KW; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Mori M; Research Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan., Amarasinghe GK; Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Cheng SM; Division of Public Health Laboratory Sciences, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Poon LL; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Division of Public Health Laboratory Sciences, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Peiris M; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Division of Public Health Laboratory Sciences, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Valkenburg SA; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. sophie.v@unimelb.edu.au.; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Australia. sophie.v@unimelb.edu.au.
Source: Nature communications [Nat Commun] 2025 Aug 23; Vol. 16 (1), pp. 7879. Date of Electronic Publication: 2025 Aug 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: SARS-CoV-2 antibody responses in children exhibit higher FcR engagement and avidity than in adults.
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  Data: <searchLink fieldCode="AU" term="%22Cohen+CA%22">Cohen CA</searchLink>; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Grzelak+L%22">Grzelak L</searchLink>; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Chiu+SS%22">Chiu SS</searchLink>; Department of Paediatric and Adolescent Medicine, The University of Hong Kong and Queen Mary Hospital, Hospital Authority of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Hui+DS%22">Hui DS</searchLink>; Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Kwan+MY%22">Kwan MY</searchLink>; Department of Paediatric and Adolescent Medicine, Hong Kong Hospital Authority Infectious Disease Centre, Princess Margaret Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Tsang+OT%22">Tsang OT</searchLink>; Infectious Diseases Centre, Princess Margaret Hospital, Hospital Authority of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chan+WH%22">Chan WH</searchLink>; Department of Paediatrics, Queen Elizabeth Hospital, Hospital Authority of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Yau+YS%22">Yau YS</searchLink>; Department of Paediatrics, Queen Elizabeth Hospital, Hospital Authority of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Lee+KW%22">Lee KW</searchLink>; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Mori+M%22">Mori M</searchLink>; Research Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Amarasinghe+GK%22">Amarasinghe GK</searchLink>; Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Cheng+SM%22">Cheng SM</searchLink>; Division of Public Health Laboratory Sciences, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Poon+LL%22">Poon LL</searchLink>; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Division of Public Health Laboratory Sciences, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Peiris+M%22">Peiris M</searchLink>; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Division of Public Health Laboratory Sciences, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Valkenburg+SA%22">Valkenburg SA</searchLink>; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. sophie.v@unimelb.edu.au.; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Australia. sophie.v@unimelb.edu.au.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Aug 23; Vol. 16 (1), pp. 7879. <i>Date of Electronic Publication: </i>2025 Aug 23.
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