Ankyrin-B modulates mitochondrial fission in skeletal muscle and is required for optimal endurance exercise capacity.

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Title: Ankyrin-B modulates mitochondrial fission in skeletal muscle and is required for optimal endurance exercise capacity.
Authors: Voos KM; Department of Cell and Developmental Biology, Perelman School of Medicine. University of Pennsylvania, Philadelphia, PA, USA.; Department of Cell Biology and Physiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Tzeng J; Department of Cell and Developmental Biology, Perelman School of Medicine. University of Pennsylvania, Philadelphia, PA, USA.; Department of Cell Biology and Physiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Patel P; Department of Cell and Developmental Biology, Perelman School of Medicine. University of Pennsylvania, Philadelphia, PA, USA., Rubinsky S; Department of Cell and Developmental Biology, Perelman School of Medicine. University of Pennsylvania, Philadelphia, PA, USA., Choi HE; Department of Cell Biology and Physiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Pharr T; Department of Cell Biology and Physiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sookram S; Department of Cell and Developmental Biology, Perelman School of Medicine. University of Pennsylvania, Philadelphia, PA, USA., Baur JA; Department of Physiology and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine. University of Pennsylvania, Philadelphia, PA, USA., Soderblom EJ; Department of Cell Biology, Duke University School of Medicine, Duke University, Durham, NC, USA., Lorenzo DN; Department of Cell and Developmental Biology, Perelman School of Medicine. University of Pennsylvania, Philadelphia, PA, USA. damaris.lorenzo@pennmedicine.upenn.edu.; Department of Cell Biology and Physiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. damaris.lorenzo@pennmedicine.upenn.edu.; Department of Physiology and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine. University of Pennsylvania, Philadelphia, PA, USA. damaris.lorenzo@pennmedicine.upenn.edu.
Source: Nature communications [Nat Commun] 2025 Aug 25; Vol. 16 (1), pp. 7671. Date of Electronic Publication: 2025 Aug 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-62977-3