Revealing the biophysics of lamina-associated domain formation by integrating theoretical modeling and high-resolution imaging.
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| Title: | Revealing the biophysics of lamina-associated domain formation by integrating theoretical modeling and high-resolution imaging. |
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| Authors: | Dhankhar M; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, USA., Guo Z; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Philadelphia, PA, USA., Kant A; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, USA., Basir R; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, USA., Joshi R; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, USA., Vinayak V; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, USA., Heo SC; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.; McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Translational Musculoskeletal Research Centre, Corporal Michael J, Crescenz VA Medical Centre, Philadelphia, PA, USA., Mauck RL; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.; McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Translational Musculoskeletal Research Centre, Corporal Michael J, Crescenz VA Medical Centre, Philadelphia, PA, USA., Lakadamyali M; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Shenoy VB; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA. vshenoy@upenn.edu.; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, USA. vshenoy@upenn.edu.; Department of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Philadelphia, PA, USA. vshenoy@upenn.edu. |
| Source: | Nature communications [Nat Commun] 2025 Aug 25; Vol. 16 (1), pp. 7909. Date of Electronic Publication: 2025 Aug 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-63244-1 |
