Analysis of Long-term Follow-up of a Randomized Clinical Trial With Departures From Assigned Treatments: Estimation of Metformin Effects on Diabetes and Its Complications in the Diabetes Prevention Program Outcomes Study.

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Title: Analysis of Long-term Follow-up of a Randomized Clinical Trial With Departures From Assigned Treatments: Estimation of Metformin Effects on Diabetes and Its Complications in the Diabetes Prevention Program Outcomes Study.
Authors: Knowler WC; Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, The George Washington University, Rockville, MD., Pan Q; Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, The George Washington University, Rockville, MD., Shu S; Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, The George Washington University, Rockville, MD., Tripputi MT; Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, The George Washington University, Rockville, MD., Dabelea D; Departments of Pediatrics and Epidemiology and Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO., Edelstein SL; Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, The George Washington University, Rockville, MD., Kahn SE; Division of Metabolism, Endocrinology and Nutrition, University of Washington, and VA Puget Sound Health Care System, Seattle, WA., Kuo S; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI., Luchsinger JA; Departments of Medicine and Epidemiology, Columbia University Irving Medical Center, New York, NY., Shah V; Department of Internal Medicine, Health Sciences Center, University of New Mexico, Albuquerque, NM., Wallia A; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL., Temprosa M; Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, The George Washington University, Rockville, MD.
Corporate Authors: Diabetes Prevention Program Research Group
Source: Diabetes care [Diabetes Care] 2025 Oct 01; Vol. 48 (10), pp. 1668-1675.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 7805975 Publication Model: Print Cited Medium: Internet ISSN: 1935-5548 (Electronic) Linking ISSN: 01495992 NLM ISO Abbreviation: Diabetes Care Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1935-5548
DOI:10.2337/dci25-0032