Differential role of C-terminal truncations on alpha-synuclein pathology and Lewy body formation.
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| Title: | Differential role of C-terminal truncations on alpha-synuclein pathology and Lewy body formation. |
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| Authors: | Mahul-Mellier AL; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.; UPDANGELO, Institute of Bioengineering and Global Health Institute, EPFL,, Lausanne, Switzerland., Altay MF; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.; Stanford Medicine, Department of Neurology and Neurological Sciences, Palo Alto, CA, USA., Maharjan N; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Ait-Bouziad N; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Chiki A; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Jagannath S; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Limorenko G; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Novello S; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Ricci J; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Jasiqi Y; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.; UPDANGELO, Institute of Bioengineering and Global Health Institute, EPFL,, Lausanne, Switzerland., Vingill S; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Wade-Martins R; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Holton J; Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK., Strand C; Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK., Haikal C; Neural Plasticity and Repair Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, Lund, Sweden., Li JY; Neural Plasticity and Repair Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, Lund, Sweden.; Institute of Health Sciences, China Medical University, Shenyang, China., Hamelin R; Proteomic Core Facility and Technology Platform, EPFL, Lausanne, Switzerland., Croisier M; BioEM Core Facility and Technology Platform, EPFL, Lausanne, Switzerland., Knott G; BioEM Core Facility and Technology Platform, EPFL, Lausanne, Switzerland., Mairet-Coello G; UCB Biopharma SPRL, Braine-l'Alleud, Belgium., Weerens L; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.; UCB Biopharma SPRL, Braine-l'Alleud, Belgium., Michel A; UCB Biopharma SPRL, Braine-l'Alleud, Belgium., Downey P; UCB Biopharma SPRL, Braine-l'Alleud, Belgium., Citron M; UCB Biopharma SPRL, Braine-l'Alleud, Belgium., Lashuel HA; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. hilal.lashuel@epfl.ch.; Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar. hilal.lashuel@epfl.ch.; Department of Neurology, Weill Cornell Medicine, New York, NY, USA. hilal.lashuel@epfl.ch. |
| Source: | NPJ Parkinson's disease [NPJ Parkinsons Dis] 2025 Aug 26; Vol. 11 (1), pp. 261. Date of Electronic Publication: 2025 Aug 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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