[Immunization of Mice with the pVAXrbd DNA Vaccine by Jet Injection Induces a Stronger Immune Response and Protection against SARS-CoV-2 Compared to Intramuscular Injection by Syringe].

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Title: [Immunization of Mice with the pVAXrbd DNA Vaccine by Jet Injection Induces a Stronger Immune Response and Protection against SARS-CoV-2 Compared to Intramuscular Injection by Syringe].
Authors: Kisakov DN; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.; def_2003@mail.ru., Borgoyakova MB; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia., Kisakova LA; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia., Starostina EV; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia., Pyankov OV; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia., Zaykovskaya AV; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia., Taranov OS; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia., Ivleva EK; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia., Rudometova NB; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia., Yakovlev VA; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia., Tigeeva EV; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia., Azaev MS; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia., Belyakov IM; Moscow Synergy Financial-Industrial University, Moscow, 129090 Russia., Rudometov AP; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia., Ilyichev AA; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia., Karpenko LI; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.
Source: Molekuliarnaia biologiia [Mol Biol (Mosk)] 2025 May-Jun; Vol. 59 (3), pp. 453-468.
Publication Type: Journal Article; Comparative Study; English Abstract
Journal Info: Publisher: Izdatelstvo Nauka Country of Publication: Russia (Federation) NLM ID: 0105454 Publication Model: Print Cited Medium: Print ISSN: 0026-8984 (Print) Linking ISSN: 00268984 NLM ISO Abbreviation: Mol Biol (Mosk) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: [Immunization of Mice with the pVAXrbd DNA Vaccine by Jet Injection Induces a Stronger Immune Response and Protection against SARS-CoV-2 Compared to Intramuscular Injection by Syringe].
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  Data: <searchLink fieldCode="AU" term="%22Kisakov+DN%22">Kisakov DN</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.; def_2003@mail.ru.<br /><searchLink fieldCode="AU" term="%22Borgoyakova+MB%22">Borgoyakova MB</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.<br /><searchLink fieldCode="AU" term="%22Kisakova+LA%22">Kisakova LA</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.<br /><searchLink fieldCode="AU" term="%22Starostina+EV%22">Starostina EV</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.<br /><searchLink fieldCode="AU" term="%22Pyankov+OV%22">Pyankov OV</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.<br /><searchLink fieldCode="AU" term="%22Zaykovskaya+AV%22">Zaykovskaya AV</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.<br /><searchLink fieldCode="AU" term="%22Taranov+OS%22">Taranov OS</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.<br /><searchLink fieldCode="AU" term="%22Ivleva+EK%22">Ivleva EK</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.<br /><searchLink fieldCode="AU" term="%22Rudometova+NB%22">Rudometova NB</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.<br /><searchLink fieldCode="AU" term="%22Yakovlev+VA%22">Yakovlev VA</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.<br /><searchLink fieldCode="AU" term="%22Tigeeva+EV%22">Tigeeva EV</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.<br /><searchLink fieldCode="AU" term="%22Azaev+MS%22">Azaev MS</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.<br /><searchLink fieldCode="AU" term="%22Belyakov+IM%22">Belyakov IM</searchLink>; Moscow Synergy Financial-Industrial University, Moscow, 129090 Russia.<br /><searchLink fieldCode="AU" term="%22Rudometov+AP%22">Rudometov AP</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.<br /><searchLink fieldCode="AU" term="%22Ilyichev+AA%22">Ilyichev AA</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.<br /><searchLink fieldCode="AU" term="%22Karpenko+LI%22">Karpenko LI</searchLink>; Vector State Scientific Center of Virology and Biotechnology Vector, Rospotrebnadzor, Center for Genomic Research of the World Level of Biosafety and Technological Independence, Federal Scientific and Technical Program for Development of Genetic Technologies, Koltsovo, Novosibirsk oblast, 630559 Russia.
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