Antidepressants stimulate lipoprotein(a) macropinocytosis via serotonin-enhanced cell surface binding.

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Title: Antidepressants stimulate lipoprotein(a) macropinocytosis via serotonin-enhanced cell surface binding.
Authors: Deo N; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand; HeartOtago, University of Otago, Dunedin, New Zealand., Siddiqui H; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand; HeartOtago, University of Otago, Dunedin, New Zealand., Peppercorn K; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand; HeartOtago, University of Otago, Dunedin, New Zealand., Madani G; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand; HeartOtago, University of Otago, Dunedin, New Zealand., Rutherford-Blyth A; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand; HeartOtago, University of Otago, Dunedin, New Zealand., Rutledge M; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand; HeartOtago, University of Otago, Dunedin, New Zealand., Williams MJA; HeartOtago, University of Otago, Dunedin, New Zealand; Department of Medicine, Otago Medical School, University of Otago, Dunedin, New Zealand., McCormick SPA; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand; HeartOtago, University of Otago, Dunedin, New Zealand. Electronic address: sally.mcormick@otago.ac.nz., Redpath GMI; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand; HeartOtago, University of Otago, Dunedin, New Zealand; Department of Molecular Medicine and EMBL Australia Node in Single Molecule Science, School of Biomedical Sciences, University of New South Wales, Sydney, Australia. Electronic address: g.redpath@unsw.edu.au.
Source: Journal of lipid research [J Lipid Res] 2025 Oct; Vol. 66 (10), pp. 100889. Date of Electronic Publication: 2025 Aug 25.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0376606 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-7262 (Electronic) Linking ISSN: 00222275 NLM ISO Abbreviation: J Lipid Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1539-7262
DOI:10.1016/j.jlr.2025.100889