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Comparative effectiveness and safety of tofacitinib and filgotinib in patients with ulcerative colitis: A propensity score-weighted cohort study.

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Title: Comparative effectiveness and safety of tofacitinib and filgotinib in patients with ulcerative colitis: A propensity score-weighted cohort study.
Authors: Macaluso FS; Inflammatory bowel disease Unit, A.O.O.R. 'Villa Sofia-Cervello', Hospital, Viale Strasburgo 233, Palermo 90146, Italy. Electronic address: fsmacaluso@gmail.com., Fries W; Inflammatory bowel disease Unit, A.O.U. Policlinico 'G. Martino', Messina, Italy., Viola A; Inflammatory bowel disease Unit, A.O.U. Policlinico 'G. Martino', Messina, Italy., De Francesco C; Inflammatory bowel disease Unit, A.O.U. Policlinico 'G. Martino', Messina, Italy., Belluardo N; Gastroenterology Unit, A.O. 'Guzzardi', Vittoria, Italy., Giangreco E; Gastroenterology Unit, A.O. 'Guzzardi', Vittoria, Italy., Cappello M; Gastroenterology and Hepatology Unit, PROMISE, A.O.U. Policlinico 'P. Giaccone', Palermo, Italy., Ajovalasit R; Gastroenterology and Hepatology Unit, PROMISE, A.O.U. Policlinico 'P. Giaccone', Palermo, Italy., Mocciaro F; Gastroenterology and Endoscopy Unit, A.R.N.A.S. 'Civico Di Cristina Benfratelli', Palermo, Italy., Scrivo B; Gastroenterology and Endoscopy Unit, A.R.N.A.S. 'Civico Di Cristina Benfratelli', Palermo, Italy., Privitera AC; Inflammatory Bowel Disease Unit, A.O. 'Cannizzaro', Catania, Italy., Distefano ME; Inflammatory Bowel Disease Unit, A.O. 'Cannizzaro', Catania, Italy., Vitello A; Gastroenterology Unit, A.O.O.R. 'S. Elia- M. Raimondi', Caltanissetta, Italy., Ferracane C; Gastroenterology Unit, A.O. 'Vittorio Emanuele', Catania, Italy., Muscarella S; Gastroenterology and Endoscopy Unit, A.O. 'S. Antonio Abate', Trapani, Italy., Li Voti R; Inflammatory bowel disease Unit, A.O.O.R. 'Villa Sofia-Cervello', Hospital, Viale Strasburgo 233, Palermo 90146, Italy., Mistretta G; Inflammatory bowel disease Unit, A.O.O.R. 'Villa Sofia-Cervello', Hospital, Viale Strasburgo 233, Palermo 90146, Italy., Renna S; Inflammatory bowel disease Unit, A.O.O.R. 'Villa Sofia-Cervello', Hospital, Viale Strasburgo 233, Palermo 90146, Italy., Casà A; Inflammatory bowel disease Unit, A.O.O.R. 'Villa Sofia-Cervello', Hospital, Viale Strasburgo 233, Palermo 90146, Italy., Ventimiglia M; Directorate General of Medical Device and Pharmaceutical Service, Italian Ministry of Health, Rome, Italy., Orlando A; Inflammatory bowel disease Unit, A.O.O.R. 'Villa Sofia-Cervello', Hospital, Viale Strasburgo 233, Palermo 90146, Italy.
Corporate Authors: Sicilian Network for Inflammatory Bowel Disease (SN-IBD)
Source: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver [Dig Liver Dis] 2025 Nov; Vol. 57 (11), pp. 2109-2113. Date of Electronic Publication: 2025 Aug 26.
Publication Type: Journal Article; Multicenter Study; Comparative Study
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 100958385 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3562 (Electronic) Linking ISSN: 15908658 NLM ISO Abbreviation: Dig Liver Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Comparative effectiveness and safety of tofacitinib and filgotinib in patients with ulcerative colitis: A propensity score-weighted cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Macaluso+FS%22">Macaluso FS</searchLink>; Inflammatory bowel disease Unit, A.O.O.R. 'Villa Sofia-Cervello', Hospital, Viale Strasburgo 233, Palermo 90146, Italy. Electronic address: fsmacaluso@gmail.com.<br /><searchLink fieldCode="AU" term="%22Fries+W%22">Fries W</searchLink>; Inflammatory bowel disease Unit, A.O.U. Policlinico 'G. Martino', Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Viola+A%22">Viola A</searchLink>; Inflammatory bowel disease Unit, A.O.U. Policlinico 'G. Martino', Messina, Italy.<br /><searchLink fieldCode="AU" term="%22De+Francesco+C%22">De Francesco C</searchLink>; Inflammatory bowel disease Unit, A.O.U. Policlinico 'G. Martino', Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Belluardo+N%22">Belluardo N</searchLink>; Gastroenterology Unit, A.O. 'Guzzardi', Vittoria, Italy.<br /><searchLink fieldCode="AU" term="%22Giangreco+E%22">Giangreco E</searchLink>; Gastroenterology Unit, A.O. 'Guzzardi', Vittoria, Italy.<br /><searchLink fieldCode="AU" term="%22Cappello+M%22">Cappello M</searchLink>; Gastroenterology and Hepatology Unit, PROMISE, A.O.U. Policlinico 'P. Giaccone', Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Ajovalasit+R%22">Ajovalasit R</searchLink>; Gastroenterology and Hepatology Unit, PROMISE, A.O.U. Policlinico 'P. Giaccone', Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Mocciaro+F%22">Mocciaro F</searchLink>; Gastroenterology and Endoscopy Unit, A.R.N.A.S. 'Civico Di Cristina Benfratelli', Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Scrivo+B%22">Scrivo B</searchLink>; Gastroenterology and Endoscopy Unit, A.R.N.A.S. 'Civico Di Cristina Benfratelli', Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Privitera+AC%22">Privitera AC</searchLink>; Inflammatory Bowel Disease Unit, A.O. 'Cannizzaro', Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Distefano+ME%22">Distefano ME</searchLink>; Inflammatory Bowel Disease Unit, A.O. 'Cannizzaro', Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Vitello+A%22">Vitello A</searchLink>; Gastroenterology Unit, A.O.O.R. 'S. Elia- M. Raimondi', Caltanissetta, Italy.<br /><searchLink fieldCode="AU" term="%22Ferracane+C%22">Ferracane C</searchLink>; Gastroenterology Unit, A.O. 'Vittorio Emanuele', Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Muscarella+S%22">Muscarella S</searchLink>; Gastroenterology and Endoscopy Unit, A.O. 'S. Antonio Abate', Trapani, Italy.<br /><searchLink fieldCode="AU" term="%22Li+Voti+R%22">Li Voti R</searchLink>; Inflammatory bowel disease Unit, A.O.O.R. 'Villa Sofia-Cervello', Hospital, Viale Strasburgo 233, Palermo 90146, Italy.<br /><searchLink fieldCode="AU" term="%22Mistretta+G%22">Mistretta G</searchLink>; Inflammatory bowel disease Unit, A.O.O.R. 'Villa Sofia-Cervello', Hospital, Viale Strasburgo 233, Palermo 90146, Italy.<br /><searchLink fieldCode="AU" term="%22Renna+S%22">Renna S</searchLink>; Inflammatory bowel disease Unit, A.O.O.R. 'Villa Sofia-Cervello', Hospital, Viale Strasburgo 233, Palermo 90146, Italy.<br /><searchLink fieldCode="AU" term="%22Casà+A%22">Casà A</searchLink>; Inflammatory bowel disease Unit, A.O.O.R. 'Villa Sofia-Cervello', Hospital, Viale Strasburgo 233, Palermo 90146, Italy.<br /><searchLink fieldCode="AU" term="%22Ventimiglia+M%22">Ventimiglia M</searchLink>; Directorate General of Medical Device and Pharmaceutical Service, Italian Ministry of Health, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Orlando+A%22">Orlando A</searchLink>; Inflammatory bowel disease Unit, A.O.O.R. 'Villa Sofia-Cervello', Hospital, Viale Strasburgo 233, Palermo 90146, Italy.
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