Crystal structures of agonist-bound human cannabinoid receptor CB1.
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| Title: | Crystal structures of agonist-bound human cannabinoid receptor CB |
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| Authors: | Hua T; iHuman Institute, ShanghaiTech University, Shanghai, China.; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China., Vemuri K; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA, USA.; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA., Nikas SP; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA, USA.; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA., Wu Y; iHuman Institute, ShanghaiTech University, Shanghai, China., Qu L; iHuman Institute, ShanghaiTech University, Shanghai, China.; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China., Pu M; iHuman Institute, ShanghaiTech University, Shanghai, China., Korde A; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA, USA.; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA., Jiang S; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA, USA.; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA., Ho JH; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, USA., Han GW; Bridge Institute, University of Southern California, Los Angeles, CA, USA.; Department of Chemistry, University of Southern California, Los Angeles, CA, USA., Ding K; iHuman Institute, ShanghaiTech University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Li X; Complex Systems Division, Beijing Computational Science Research Center, Beijing, China., Liu H; Complex Systems Division, Beijing Computational Science Research Center, Beijing, China., Hanson MA; GPCR Consortium, San Marcos, CA, USA., Zhao S; iHuman Institute, ShanghaiTech University, Shanghai, China. zhaosw@shanghaitech.edu.cn.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China. zhaosw@shanghaitech.edu.cn., Bohn LM; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, USA. Laura.bohn@ufl.edu., Makriyannis A; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA, USA. a.makriyannis@neu.edu.; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA. a.makriyannis@neu.edu., Stevens RC; iHuman Institute, ShanghaiTech University, Shanghai, China.; Bridge Institute, University of Southern California, Los Angeles, CA, USA.; Department of Chemistry, University of Southern California, Los Angeles, CA, USA.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Liu ZJ; iHuman Institute, ShanghaiTech University, Shanghai, China. liuzhj@shanghaitech.edu.cn.; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China. liuzhj@shanghaitech.edu.cn.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China. liuzhj@shanghaitech.edu.cn. |
| Source: | Nature [Nature] 2025 Oct; Vol. 646 (8085), pp. 754-758. Date of Electronic Publication: 2025 Aug 27. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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