Interferon-α Nasal Spray Prophylaxis Reduces COVID-19 in Cancer Patients: A Randomized, Double-Blinded, Placebo-Controlled Trial.
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| Title: | Interferon-α Nasal Spray Prophylaxis Reduces COVID-19 in Cancer Patients: A Randomized, Double-Blinded, Placebo-Controlled Trial. |
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| Authors: | Yong MK; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Infectious Diseases, Royal Melbourne Hospital, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Thursky K; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Health Services Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Crane M; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Spelman T; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Health Services Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Mahar RK; Biostatistics Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.; Methods and Implementation Support for Clinical and Health (MISCH) Research Hub, The University of Melbourne, Melbourne, Victoria, Australia.; Clinical Epidemiology and Biostatistics Unit, Murdoch Children's Research Institute, Parkville, Victoria, Australia., Simpson JA; Biostatistics Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.; Methods and Implementation Support for Clinical and Health (MISCH) Research Hub, The University of Melbourne, Melbourne, Victoria, Australia., Scott AM; Department of Molecular Imaging and Therapy, Austin Health, Heidelberg, Victoria, Australia.; Olivia Newton-John Cancer Research Institute, Tumour Targeting Laboratory, Heidelberg, Victoria, Australia.; Faculty of Medicine, University of Melbourne, Melbourne, Victoria, Australia.; School of Cancer Medicine, LaTrobe University, Melbourne, Victoria, Australia., Harrison SJ; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Victoria, Australia., Szer J; Faculty of Medicine, University of Melbourne, Melbourne, Victoria, Australia.; Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Victoria, Australia., Pellegrini M; Walter and Eliza Hall Institute of Medical Research, Division of Infectious Diseases and Immune Defence, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.; Centenary Institute, Executive Director, Camperdown, New South Wales, Australia.; Faculty of Heath and Medical Sciences, University of Sydney, Camperdown, New South Wales, Australia., Lingaratnam S; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; Pharmacy Department, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Pang KC; Clinical Sciences, Murdoch Children's Research Institute, Parkville, Victoria, Australia.; Department of Adolescent Medicine, Royal Children's Hospital, Parkville, Victoria, Australia.; Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia., Tennakoon S; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Sim BZ; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Blyth E; Department of Haematology, Westmead Hospital, Westmead, New South Wales, Australia.; Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia., Gan HK; Department of Oncology, Austin Hospital, Heidelberg, Victoria, Australia., Quach H; Faculty of Medicine, University of Melbourne, Melbourne, Victoria, Australia.; Department of Haematology, St Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia., McIntosh MP; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Victoria, Australia., Page H; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Infectious Diseases, Royal Melbourne Hospital, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Woolstencroft R; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Infectious Diseases, Royal Melbourne Hospital, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Slavin M; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Infectious Diseases, Royal Melbourne Hospital, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. |
| Source: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2026 Feb 25; Vol. 82 (2), pp. e208-e216. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE; In Process |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40874769 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Interferon-α Nasal Spray Prophylaxis Reduces COVID-19 in Cancer Patients: A Randomized, Double-Blinded, Placebo-Controlled Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Yong+MK%22">Yong MK</searchLink>; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Infectious Diseases, Royal Melbourne Hospital, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Thursky+K%22">Thursky K</searchLink>; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Health Services Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Crane+M%22">Crane M</searchLink>; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Spelman+T%22">Spelman T</searchLink>; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Health Services Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Mahar+RK%22">Mahar RK</searchLink>; Biostatistics Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.; Methods and Implementation Support for Clinical and Health (MISCH) Research Hub, The University of Melbourne, Melbourne, Victoria, Australia.; Clinical Epidemiology and Biostatistics Unit, Murdoch Children's Research Institute, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Simpson+JA%22">Simpson JA</searchLink>; Biostatistics Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.; Methods and Implementation Support for Clinical and Health (MISCH) Research Hub, The University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Scott+AM%22">Scott AM</searchLink>; Department of Molecular Imaging and Therapy, Austin Health, Heidelberg, Victoria, Australia.; Olivia Newton-John Cancer Research Institute, Tumour Targeting Laboratory, Heidelberg, Victoria, Australia.; Faculty of Medicine, University of Melbourne, Melbourne, Victoria, Australia.; School of Cancer Medicine, LaTrobe University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Harrison+SJ%22">Harrison SJ</searchLink>; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Szer+J%22">Szer J</searchLink>; Faculty of Medicine, University of Melbourne, Melbourne, Victoria, Australia.; Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Pellegrini+M%22">Pellegrini M</searchLink>; Walter and Eliza Hall Institute of Medical Research, Division of Infectious Diseases and Immune Defence, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.; Centenary Institute, Executive Director, Camperdown, New South Wales, Australia.; Faculty of Heath and Medical Sciences, University of Sydney, Camperdown, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Lingaratnam+S%22">Lingaratnam S</searchLink>; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; Pharmacy Department, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Pang+KC%22">Pang KC</searchLink>; Clinical Sciences, Murdoch Children's Research Institute, Parkville, Victoria, Australia.; Department of Adolescent Medicine, Royal Children's Hospital, Parkville, Victoria, Australia.; Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Tennakoon+S%22">Tennakoon S</searchLink>; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Sim+BZ%22">Sim BZ</searchLink>; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Blyth+E%22">Blyth E</searchLink>; Department of Haematology, Westmead Hospital, Westmead, New South Wales, Australia.; Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Gan+HK%22">Gan HK</searchLink>; Department of Oncology, Austin Hospital, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Quach+H%22">Quach H</searchLink>; Faculty of Medicine, University of Melbourne, Melbourne, Victoria, Australia.; Department of Haematology, St Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22McIntosh+MP%22">McIntosh MP</searchLink>; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Page+H%22">Page H</searchLink>; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Infectious Diseases, Royal Melbourne Hospital, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Woolstencroft+R%22">Woolstencroft R</searchLink>; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Infectious Diseases, Royal Melbourne Hospital, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Slavin+M%22">Slavin M</searchLink>; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Infectious Diseases, Royal Melbourne Hospital, Melbourne, Victoria, Australia.; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229203213%22">Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</searchLink> [Clin Infect Dis] 2026 Feb 25; Vol. 82 (2), pp. e208-e216. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9203213 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1537-6591 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210584838%22">10584838 </searchLink><i>NLM ISO Abbreviation: </i>Clin Infect Dis <i>Subsets: </i>MEDLINE; In Process |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1093/cid/ciaf409 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e208 Titles: – TitleFull: Interferon-α Nasal Spray Prophylaxis Reduces COVID-19 in Cancer Patients: A Randomized, Double-Blinded, Placebo-Controlled Trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Yong MK – PersonEntity: Name: NameFull: Thursky K – PersonEntity: Name: NameFull: Crane M – PersonEntity: Name: NameFull: Spelman T – PersonEntity: Name: NameFull: Mahar RK – PersonEntity: Name: NameFull: Simpson JA – PersonEntity: Name: NameFull: Scott AM – PersonEntity: Name: NameFull: Harrison SJ – PersonEntity: Name: NameFull: Szer J – PersonEntity: Name: NameFull: Pellegrini M – PersonEntity: Name: NameFull: Lingaratnam S – PersonEntity: Name: NameFull: Pang KC – PersonEntity: Name: NameFull: Tennakoon S – PersonEntity: Name: NameFull: Sim BZ – PersonEntity: Name: NameFull: Blyth E – PersonEntity: Name: NameFull: Gan HK – PersonEntity: Name: NameFull: Quach H – PersonEntity: Name: NameFull: McIntosh MP – PersonEntity: Name: NameFull: Page H – PersonEntity: Name: NameFull: Woolstencroft R – PersonEntity: Name: NameFull: Slavin M IsPartOfRelationships: – BibEntity: Dates: – D: 25 M: 02 Text: 2026 Feb 25 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1537-6591 Numbering: – Type: volume Value: 82 – Type: issue Value: 2 Titles: – TitleFull: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Type: main |
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