Amelioration of intestinal ischemia reperfusion injury by carvedilol via regulation of eNOS/VEGF-A and inflammasome/ IL1β/ TNFα pathways.

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Title: Amelioration of intestinal ischemia reperfusion injury by carvedilol via regulation of eNOS/VEGF-A and inflammasome/ IL1β/ TNFα pathways.
Authors: Refaie MMM; Department of Medical Pharmacology, Faculty of Medicine, Minia University, 61511, El-Minia, Egypt; Faculty of Medicine, Minia National University, Minia, Egypt., Abdel-Hakeem EA; Department of Medical Physiology, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt; Faculty of Medicine, Minia National University, Minia, Egypt. Electronic address: shady@mu.edu.eg., Shehata S; Department of Cardiology, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt., Elsaghir SMM; Department of Internal Medicine, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt., Gaber Ibrahim MF; Department of Histology and Cell Biology, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt; Faculty of Physical Therapy, Lotus University, El-Minia, 61768, Egypt; Faculty of Medicine, Minia National University, Minia, Egypt. Electronic address: manar.fouli@lum.edu.eg., Mustafa Ahmed NZ; Department of Medical Biochemistry, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt; Department of Biochemistry, Faculty of Medicine, Al-Baha University, Albaha, 65525, Saudi Arabia., Elsayed SH; Department of Medical Biochemistry, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt; Faculty of Medicine, Minia National University, Minia, Egypt., Shawky HA; Anatomy and Embryology Department, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt; Faculty of Medicine, Minia National University, Minia, Egypt., Elroby Ali DM; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt.
Source: European journal of pharmacology [Eur J Pharmacol] 2025 Oct 15; Vol. 1005, pp. 178097. Date of Electronic Publication: 2025 Aug 26.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Amelioration of intestinal ischemia reperfusion injury by carvedilol via regulation of eNOS/VEGF-A and inflammasome/ IL1β/ TNFα pathways.
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  Data: <searchLink fieldCode="AU" term="%22Refaie+MMM%22">Refaie MMM</searchLink>; Department of Medical Pharmacology, Faculty of Medicine, Minia University, 61511, El-Minia, Egypt; Faculty of Medicine, Minia National University, Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Abdel-Hakeem+EA%22">Abdel-Hakeem EA</searchLink>; Department of Medical Physiology, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt; Faculty of Medicine, Minia National University, Minia, Egypt. Electronic address: shady@mu.edu.eg.<br /><searchLink fieldCode="AU" term="%22Shehata+S%22">Shehata S</searchLink>; Department of Cardiology, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt.<br /><searchLink fieldCode="AU" term="%22Elsaghir+SMM%22">Elsaghir SMM</searchLink>; Department of Internal Medicine, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt.<br /><searchLink fieldCode="AU" term="%22Gaber+Ibrahim+MF%22">Gaber Ibrahim MF</searchLink>; Department of Histology and Cell Biology, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt; Faculty of Physical Therapy, Lotus University, El-Minia, 61768, Egypt; Faculty of Medicine, Minia National University, Minia, Egypt. Electronic address: manar.fouli@lum.edu.eg.<br /><searchLink fieldCode="AU" term="%22Mustafa+Ahmed+NZ%22">Mustafa Ahmed NZ</searchLink>; Department of Medical Biochemistry, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt; Department of Biochemistry, Faculty of Medicine, Al-Baha University, Albaha, 65525, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Elsayed+SH%22">Elsayed SH</searchLink>; Department of Medical Biochemistry, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt; Faculty of Medicine, Minia National University, Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Shawky+HA%22">Shawky HA</searchLink>; Anatomy and Embryology Department, Faculty of Medicine, Minia University, El-Minia, 61511, Egypt; Faculty of Medicine, Minia National University, Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Elroby+Ali+DM%22">Elroby Ali DM</searchLink>; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt.
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  Data: <searchLink fieldCode="JN" term="%221254354%22">European journal of pharmacology</searchLink> [Eur J Pharmacol] 2025 Oct 15; Vol. 1005, pp. 178097. <i>Date of Electronic Publication: </i>2025 Aug 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>1254354 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0712 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200142999%22">00142999 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Pharmacol <i>Subsets: </i>MEDLINE
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              Text: 2025 Oct 15
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