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Cardiovascular Safety of Bruton Tyrosine Kinase Inhibitors: From Ibrutinib to Next-Generation Agents.

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Title: Cardiovascular Safety of Bruton Tyrosine Kinase Inhibitors: From Ibrutinib to Next-Generation Agents.
Authors: Spadafora L; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100, Latina, Italy. luigispadafora167@gmail.com.; Division of Cardiology and Interventional Cardiology, Santa Maria Goretti Hospital, Latina, Italy. luigispadafora167@gmail.com., Russo F; Sapienza University, Rome, Italy.; Sant'Andrea Hospital, Rome, Italy., Bukowska-Olech E; Department of Laboratory Diagnostics, Poznan University of Medical Sciences, Poznan, Poland., Panichella G; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Garofalo M; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Cacciatore S; Department of Geriatrics, Orthopedics, and Rheumatology, Università Cattolica del Sacro Cuore, L.go F. Vito 1, 00168, Rome, Italy.; Fondazione Policlinico Universitario 'Agostino Gemelli' IRCCS, L.go A. Gemelli 8, 00168, Rome, Italy., Sabouret P; Heart Institute and Action Group, Pitié-Salpétrière, Sorbonne University, Paris, France., Sarto G; Cardiology Division, ICOT Istituto 'Marco Pasquali' University Hospital, 04100, Latina, Italy., Simeone B; Cardiology Division, ICOT Istituto 'Marco Pasquali' University Hospital, 04100, Latina, Italy., Rocco E; Cardiology Division, ICOT Istituto 'Marco Pasquali' University Hospital, 04100, Latina, Italy., Lauretti A; Division of Cardiology and Interventional Cardiology, Santa Maria Goretti Hospital, Latina, Italy., Versaci F; Division of Cardiology and Interventional Cardiology, Santa Maria Goretti Hospital, Latina, Italy., Zoccai GB; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100, Latina, Italy.; Maria Cecilia Hospital, GVM Care and Research, 48033, Cotignola, Italy., Colaiori I; Division of Cardiology and Interventional Cardiology, Santa Maria Goretti Hospital, Latina, Italy., Valenti V; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100, Latina, Italy.; Maria Cecilia Hospital, GVM Care and Research, 48033, Cotignola, Italy., Sciarretta S; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100, Latina, Italy.; IRCCS NeuroMed, Pozzilli, Italy., Bernardi M; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100, Latina, Italy.; Division of Cardiology and Interventional Cardiology, Santa Maria Goretti Hospital, Latina, Italy.
Source: American journal of cardiovascular drugs : drugs, devices, and other interventions [Am J Cardiovasc Drugs] 2026 Jan; Vol. 26 (1), pp. 21-34. Date of Electronic Publication: 2025 Aug 28.
Publication Type: Journal Article; Review
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 100967755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-187X (Electronic) Linking ISSN: 11753277 NLM ISO Abbreviation: Am J Cardiovasc Drugs Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Spadafora+L%22">Spadafora L</searchLink>; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100, Latina, Italy. luigispadafora167@gmail.com.; Division of Cardiology and Interventional Cardiology, Santa Maria Goretti Hospital, Latina, Italy. luigispadafora167@gmail.com.<br /><searchLink fieldCode="AU" term="%22Russo+F%22">Russo F</searchLink>; Sapienza University, Rome, Italy.; Sant'Andrea Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bukowska-Olech+E%22">Bukowska-Olech E</searchLink>; Department of Laboratory Diagnostics, Poznan University of Medical Sciences, Poznan, Poland.<br /><searchLink fieldCode="AU" term="%22Panichella+G%22">Panichella G</searchLink>; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Garofalo+M%22">Garofalo M</searchLink>; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Cacciatore+S%22">Cacciatore S</searchLink>; Department of Geriatrics, Orthopedics, and Rheumatology, Università Cattolica del Sacro Cuore, L.go F. Vito 1, 00168, Rome, Italy.; Fondazione Policlinico Universitario 'Agostino Gemelli' IRCCS, L.go A. Gemelli 8, 00168, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Sabouret+P%22">Sabouret P</searchLink>; Heart Institute and Action Group, Pitié-Salpétrière, Sorbonne University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Sarto+G%22">Sarto G</searchLink>; Cardiology Division, ICOT Istituto 'Marco Pasquali' University Hospital, 04100, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Simeone+B%22">Simeone B</searchLink>; Cardiology Division, ICOT Istituto 'Marco Pasquali' University Hospital, 04100, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Rocco+E%22">Rocco E</searchLink>; Cardiology Division, ICOT Istituto 'Marco Pasquali' University Hospital, 04100, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Lauretti+A%22">Lauretti A</searchLink>; Division of Cardiology and Interventional Cardiology, Santa Maria Goretti Hospital, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Versaci+F%22">Versaci F</searchLink>; Division of Cardiology and Interventional Cardiology, Santa Maria Goretti Hospital, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Zoccai+GB%22">Zoccai GB</searchLink>; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100, Latina, Italy.; Maria Cecilia Hospital, GVM Care and Research, 48033, Cotignola, Italy.<br /><searchLink fieldCode="AU" term="%22Colaiori+I%22">Colaiori I</searchLink>; Division of Cardiology and Interventional Cardiology, Santa Maria Goretti Hospital, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Valenti+V%22">Valenti V</searchLink>; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100, Latina, Italy.; Maria Cecilia Hospital, GVM Care and Research, 48033, Cotignola, Italy.<br /><searchLink fieldCode="AU" term="%22Sciarretta+S%22">Sciarretta S</searchLink>; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100, Latina, Italy.; IRCCS NeuroMed, Pozzilli, Italy.<br /><searchLink fieldCode="AU" term="%22Bernardi+M%22">Bernardi M</searchLink>; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100, Latina, Italy.; Division of Cardiology and Interventional Cardiology, Santa Maria Goretti Hospital, Latina, Italy.
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