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Analyses of GWAS and Sub-Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic Risk.

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Title: Analyses of GWAS and Sub-Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic Risk.
Authors: Chen R; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Siciliano B; The Graduate Program in Molecular and Systems Pharmacology, Laney Graduate School, Emory University, Atlanta, GA, 30322, USA., Wang Q; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Xu C; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, 30322, USA., Wei Q; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Yang H; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Sutcliffe JS; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Jiang Y; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Ji Y; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Liu C; Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, 13210, USA., Cheng F; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.; Cleveland Clinic Genome Center and Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44106, USA., Cook EH; Department of Psychiatry, University of Illinois, Chicago, IL, 60612, USA., Cox NJ; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Zhong X; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Wen Z; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, 30322, USA.; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA, 30322, USA.; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, 30322, USA., Li B; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Oct; Vol. 12 (39), pp. e08519. Date of Electronic Publication: 2025 Aug 29.
Publication Type: Journal Article
Journal Info: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Analyses of GWAS and Sub-Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic Risk.
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  Data: <searchLink fieldCode="AU" term="%22Chen+R%22">Chen R</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Siciliano+B%22">Siciliano B</searchLink>; The Graduate Program in Molecular and Systems Pharmacology, Laney Graduate School, Emory University, Atlanta, GA, 30322, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Xu+C%22">Xu C</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, 30322, USA.<br /><searchLink fieldCode="AU" term="%22Wei+Q%22">Wei Q</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Sutcliffe+JS%22">Sutcliffe JS</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Ji+Y%22">Ji Y</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, 13210, USA.<br /><searchLink fieldCode="AU" term="%22Cheng+F%22">Cheng F</searchLink>; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.; Cleveland Clinic Genome Center and Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44106, USA.<br /><searchLink fieldCode="AU" term="%22Cook+EH%22">Cook EH</searchLink>; Department of Psychiatry, University of Illinois, Chicago, IL, 60612, USA.<br /><searchLink fieldCode="AU" term="%22Cox+NJ%22">Cox NJ</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Zhong+X%22">Zhong X</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.<br /><searchLink fieldCode="AU" term="%22Wen+Z%22">Wen Z</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, 30322, USA.; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA, 30322, USA.; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, 30322, USA.<br /><searchLink fieldCode="AU" term="%22Li+B%22">Li B</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
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  Data: <searchLink fieldCode="JN" term="%22101664569%22">Advanced science (Weinheim, Baden-Wurttemberg, Germany)</searchLink> [Adv Sci (Weinh)] 2025 Oct; Vol. 12 (39), pp. e08519. <i>Date of Electronic Publication: </i>2025 Aug 29.
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        Value: 10.1002/advs.202508519
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