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State of the art biology, progression, and clinical management of monoclonal B-cell lymphocytosis (MBL): consensus report from the Intercepting Blood Cancers Workshop Committee.

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Title: State of the art biology, progression, and clinical management of monoclonal B-cell lymphocytosis (MBL): consensus report from the Intercepting Blood Cancers Workshop Committee.
Authors: Ryan CE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Ahn IE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Sekar A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Rawstron A; Leeds Teaching Hospitals NHS Trust, Leeds, UK., Almeida J; Translational and Clinical Research Program, Cancer Research Center (IBMCC; CSIC-University of Salamanca); Cytometry Service (NUCLEUS); Department of Medicine, and ECRIN M3 Consortium, University of Salamanca, Salamanca, Spain.; Instituto de Investigación Biomédica de Salamanca, and ECRIN M3 Consortium, Salamanca, Spain; and CIBERONC, Institute of Health Carlos III., Madrid, Spain., Martin-Subero I; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Parry EM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Alcoceba M; Instituto de Investigación Biomédica de Salamanca, and ECRIN M3 Consortium, Salamanca, Spain; and CIBERONC, Institute of Health Carlos III., Madrid, Spain.; Department of Hematology, University Hospital of Salamanca, Salamanca, Spain., Calado DP; The Francis Crick Institute, London, UK., Orfao A; Translational and Clinical Research Program, Cancer Research Center (IBMCC; CSIC-University of Salamanca); Cytometry Service (NUCLEUS); Department of Medicine, and ECRIN M3 Consortium, University of Salamanca, Salamanca, Spain.; Instituto de Investigación Biomédica de Salamanca, and ECRIN M3 Consortium, Salamanca, Spain; and CIBERONC, Institute of Health Carlos III., Madrid, Spain., Langerak AW; Department of Immunology, Laboratory Medical Immunology, Erasmus MC, Rotterdam, the Netherlands., Veelken H; Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands., Langerbeins P; Department I of Internal Medicine and German CLL Study Group, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Stephens DM; University of North Carolina Chapel Hill School of Medicine, Chapel Hill, NC, USA., Parikh SA; Division of Hematology, Mayo Clinic, Rochester, MN, USA., Niemann CU; Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Roulland S; Aix-Marseille University, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France., Stamatopoulos K; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece., Slager SL; Division of Hematology, Mayo Clinic, Rochester, MN, USA.; Division of Computational Biology, Mayo Clinic, Rochester, MN, USA., Shanafelt T; Stanford University School of Medicine, Stanford, CA, USA., Ghia P; Università Vita-Salute San Raffaele, Milano, Italy.; IRCCS Ospedale San Raffaele, Milano, Italy., Okosun J; Barts Cancer Institute, Queen Mary University of London, London, UK., Davids MS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. Matthew_Davids@DFCI.Harvard.edu.
Source: Blood cancer journal [Blood Cancer J] 2025 Aug 29; Vol. 15 (1), pp. 148. Date of Electronic Publication: 2025 Aug 29.
Publication Type: Journal Article; Consensus Statement
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-5385 (Electronic) Linking ISSN: 20445385 NLM ISO Abbreviation: Blood Cancer J Subsets: MEDLINE
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  Data: State of the art biology, progression, and clinical management of monoclonal B-cell lymphocytosis (MBL): consensus report from the Intercepting Blood Cancers Workshop Committee.
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  Data: <searchLink fieldCode="AU" term="%22Ryan+CE%22">Ryan CE</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ahn+IE%22">Ahn IE</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sekar+A%22">Sekar A</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rawstron+A%22">Rawstron A</searchLink>; Leeds Teaching Hospitals NHS Trust, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Almeida+J%22">Almeida J</searchLink>; Translational and Clinical Research Program, Cancer Research Center (IBMCC; CSIC-University of Salamanca); Cytometry Service (NUCLEUS); Department of Medicine, and ECRIN M3 Consortium, University of Salamanca, Salamanca, Spain.; Instituto de Investigación Biomédica de Salamanca, and ECRIN M3 Consortium, Salamanca, Spain; and CIBERONC, Institute of Health Carlos III., Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Martin-Subero+I%22">Martin-Subero I</searchLink>; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Parry+EM%22">Parry EM</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Alcoceba+M%22">Alcoceba M</searchLink>; Instituto de Investigación Biomédica de Salamanca, and ECRIN M3 Consortium, Salamanca, Spain; and CIBERONC, Institute of Health Carlos III., Madrid, Spain.; Department of Hematology, University Hospital of Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Calado+DP%22">Calado DP</searchLink>; The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Orfao+A%22">Orfao A</searchLink>; Translational and Clinical Research Program, Cancer Research Center (IBMCC; CSIC-University of Salamanca); Cytometry Service (NUCLEUS); Department of Medicine, and ECRIN M3 Consortium, University of Salamanca, Salamanca, Spain.; Instituto de Investigación Biomédica de Salamanca, and ECRIN M3 Consortium, Salamanca, Spain; and CIBERONC, Institute of Health Carlos III., Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Langerak+AW%22">Langerak AW</searchLink>; Department of Immunology, Laboratory Medical Immunology, Erasmus MC, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Veelken+H%22">Veelken H</searchLink>; Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Langerbeins+P%22">Langerbeins P</searchLink>; Department I of Internal Medicine and German CLL Study Group, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Stephens+DM%22">Stephens DM</searchLink>; University of North Carolina Chapel Hill School of Medicine, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Parikh+SA%22">Parikh SA</searchLink>; Division of Hematology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Niemann+CU%22">Niemann CU</searchLink>; Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Roulland+S%22">Roulland S</searchLink>; Aix-Marseille University, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Stamatopoulos+K%22">Stamatopoulos K</searchLink>; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Slager+SL%22">Slager SL</searchLink>; Division of Hematology, Mayo Clinic, Rochester, MN, USA.; Division of Computational Biology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Shanafelt+T%22">Shanafelt T</searchLink>; Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ghia+P%22">Ghia P</searchLink>; Università Vita-Salute San Raffaele, Milano, Italy.; IRCCS Ospedale San Raffaele, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Okosun+J%22">Okosun J</searchLink>; Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Davids+MS%22">Davids MS</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. Matthew_Davids@DFCI.Harvard.edu.
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