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SPANXB1 drives brain metastasis in breast cancer via MMP1 regulation: potential therapeutic insights with metformin.

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Title: SPANXB1 drives brain metastasis in breast cancer via MMP1 regulation: potential therapeutic insights with metformin.
Authors: Wang Q; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China., Wu H; School of Basic Medical Sciences, Capital Medical University, Beijing, China., Zhai Z; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China., Fang D; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China., Yang C; Department of Experimental Center for Basic Medical Teaching, School of Basic Medical Sciences, Capital Medical University, Beijing, China., Liu L; Department of Experimental Center for Basic Medical Teaching, School of Basic Medical Sciences, Capital Medical University, Beijing, China., Jia X; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China., Du B; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China., Lyu Y; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China., Zhang M; Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, China., Lu T; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China., Wang L; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China. lwang@ccmu.edu.cn., Gao Y; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China. gy1003@ccmu.edu.cn.; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China. gy1003@ccmu.edu.cn.
Source: Cell death discovery [Cell Death Discov] 2025 Aug 30; Vol. 11 (1), pp. 418. Date of Electronic Publication: 2025 Aug 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: SPANXB1 drives brain metastasis in breast cancer via MMP1 regulation: potential therapeutic insights with metformin.
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  Data: <searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wu+H%22">Wu H</searchLink>; School of Basic Medical Sciences, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhai+Z%22">Zhai Z</searchLink>; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Fang+D%22">Fang D</searchLink>; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yang+C%22">Yang C</searchLink>; Department of Experimental Center for Basic Medical Teaching, School of Basic Medical Sciences, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Department of Experimental Center for Basic Medical Teaching, School of Basic Medical Sciences, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Jia+X%22">Jia X</searchLink>; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Du+B%22">Du B</searchLink>; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Lyu+Y%22">Lyu Y</searchLink>; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+M%22">Zhang M</searchLink>; Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Lu+T%22">Lu T</searchLink>; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China. lwang@ccmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Gao+Y%22">Gao Y</searchLink>; Department of Human Anatomy, School of Basic Medical Sciences, Capital Medical University, Beijing, China. gy1003@ccmu.edu.cn.; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China. gy1003@ccmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101665035%22">Cell death discovery</searchLink> [Cell Death Discov] 2025 Aug 30; Vol. 11 (1), pp. 418. <i>Date of Electronic Publication: </i>2025 Aug 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101665035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2058-7716 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220587716%22">20587716 </searchLink><i>NLM ISO Abbreviation: </i>Cell Death Discov <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1038/s41420-025-02721-4
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