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Selective disruption of DNMT1/ELK1 interactions induces DGKI re-expression and promotes temozolomide sensitivity of MGMTmethylated/DGKImethylated glioblastoma.

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Title: Selective disruption of DNMT1/ELK1 interactions induces DGKI re-expression and promotes temozolomide sensitivity of MGMTmethylated/DGKImethylated glioblastoma.
Authors: Besson JM; Institut Des Biomolécules Max Mousseron, CNRS, UM, ENSCM IBMM-UMR 5247, 1919 Route de Mende, 34293Cedex 5, Montpellier, France., Etcheverry A; Molecular Genetics and Genomics Department, CHU Rennes, 35033, Rennes, France., Nadaradjane A; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, F-44000, Nantes, France., Bougras-Cartron G; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, F-44000, Nantes, France.; Institut de Cancérologie de L'Ouest, 44805, Saint-Herblain, France., Aubry M; INSERM, OSS (Oncogenesis Stress Signaling), UMR_S 1242, CLCC Eugene Marquis, Univ Rennes, 35000, Rennes, France., Frenel JS; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, F-44000, Nantes, France.; Institut de Cancérologie de L'Ouest, 44805, Saint-Herblain, France., Chevanieu A; Institut Des Biomolécules Max Mousseron, CNRS, UM, ENSCM IBMM-UMR 5247, 1919 Route de Mende, 34293Cedex 5, Montpellier, France., Lopez M; Institut Des Biomolécules Max Mousseron, CNRS, UM, ENSCM IBMM-UMR 5247, 1919 Route de Mende, 34293Cedex 5, Montpellier, France., Mosser J; Molecular Genetics and Genomics Department, CHU Rennes, 35033, Rennes, France.; INSERM, OSS (Oncogenesis Stress Signaling), UMR_S 1242, CLCC Eugene Marquis, Univ Rennes, 35000, Rennes, France., Cartron PF; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, F-44000, Nantes, France. pierre-francois.cartron@inserm.fr.; Institut de Cancérologie de L'Ouest, 44805, Saint-Herblain, France. pierre-francois.cartron@inserm.fr.
Source: Clinical epigenetics [Clin Epigenetics] 2025 Aug 30; Vol. 17 (1), pp. 146. Date of Electronic Publication: 2025 Aug 30.
Publication Type: Journal Article
Journal Info: Publisher: Biomed Central Country of Publication: Germany NLM ID: 101516977 Publication Model: Electronic Cited Medium: Internet ISSN: 1868-7083 (Electronic) Linking ISSN: 18687075 NLM ISO Abbreviation: Clin Epigenetics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Selective disruption of DNMT1/ELK1 interactions induces DGKI re-expression and promotes temozolomide sensitivity of MGMT<superscript>methylated</superscript>/DGKI<superscript>methylated</superscript> glioblastoma.
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  Data: <searchLink fieldCode="AU" term="%22Besson+JM%22">Besson JM</searchLink>; Institut Des Biomolécules Max Mousseron, CNRS, UM, ENSCM IBMM-UMR 5247, 1919 Route de Mende, 34293Cedex 5, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Etcheverry+A%22">Etcheverry A</searchLink>; Molecular Genetics and Genomics Department, CHU Rennes, 35033, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Nadaradjane+A%22">Nadaradjane A</searchLink>; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, F-44000, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Bougras-Cartron+G%22">Bougras-Cartron G</searchLink>; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, F-44000, Nantes, France.; Institut de Cancérologie de L'Ouest, 44805, Saint-Herblain, France.<br /><searchLink fieldCode="AU" term="%22Aubry+M%22">Aubry M</searchLink>; INSERM, OSS (Oncogenesis Stress Signaling), UMR_S 1242, CLCC Eugene Marquis, Univ Rennes, 35000, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Frenel+JS%22">Frenel JS</searchLink>; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, F-44000, Nantes, France.; Institut de Cancérologie de L'Ouest, 44805, Saint-Herblain, France.<br /><searchLink fieldCode="AU" term="%22Chevanieu+A%22">Chevanieu A</searchLink>; Institut Des Biomolécules Max Mousseron, CNRS, UM, ENSCM IBMM-UMR 5247, 1919 Route de Mende, 34293Cedex 5, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Lopez+M%22">Lopez M</searchLink>; Institut Des Biomolécules Max Mousseron, CNRS, UM, ENSCM IBMM-UMR 5247, 1919 Route de Mende, 34293Cedex 5, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Mosser+J%22">Mosser J</searchLink>; Molecular Genetics and Genomics Department, CHU Rennes, 35033, Rennes, France.; INSERM, OSS (Oncogenesis Stress Signaling), UMR_S 1242, CLCC Eugene Marquis, Univ Rennes, 35000, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Cartron+PF%22">Cartron PF</searchLink>; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, F-44000, Nantes, France. pierre-francois.cartron@inserm.fr.; Institut de Cancérologie de L'Ouest, 44805, Saint-Herblain, France. pierre-francois.cartron@inserm.fr.
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  Data: <searchLink fieldCode="JN" term="%22101516977%22">Clinical epigenetics</searchLink> [Clin Epigenetics] 2025 Aug 30; Vol. 17 (1), pp. 146. <i>Date of Electronic Publication: </i>2025 Aug 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Biomed+Central%22">Biomed Central </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101516977 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1868-7083 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218687075%22">18687075 </searchLink><i>NLM ISO Abbreviation: </i>Clin Epigenetics <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13148-025-01943-8
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      – TitleFull: Selective disruption of DNMT1/ELK1 interactions induces DGKI re-expression and promotes temozolomide sensitivity of MGMTmethylated/DGKImethylated glioblastoma.
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              Text: 2025 Aug 30
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