Downregulated miR-199a-3p in Preeclamptic Placenta-derived Exosomes from Cord Blood Hinders VEGF-induced Fetal Glomerular Dysplasia Through Inhibiting Akt1(S473) Phosphorylation via Targeting PHLPP2.

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Title: Downregulated miR-199a-3p in Preeclamptic Placenta-derived Exosomes from Cord Blood Hinders VEGF-induced Fetal Glomerular Dysplasia Through Inhibiting Akt1(S473) Phosphorylation via Targeting PHLPP2.
Authors: Jiang X; Department of Obstetrics and Gynecology, Shandong Provincial Hospital, Shandong University, Jinan, 250021, Shandong, China.; Obstetrics and Gynecology, Maternity and Child Health Care of RIZHAO, Rizhao, 276827, Shandong, China., Gu M; Department of Obstetrics and Gynecology, Shandong Provincial Hospital, Shandong University, Jinan, 250021, Shandong, China., Xie Y; Department of Obstetrics and Gynecology, Shandong Provincial Hospital, Shandong University, Jinan, 250021, Shandong, China., Li Y; Department of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China., Lv Q; Department of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China., Chen P; Department of Obstetrics and Gynecology, Shandong Provincial Hospital, Shandong University, Jinan, 250021, Shandong, China., Jing D; Department of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China., Zhou Y; Department of Obstetrics and Gynecology, Shandong Provincial Hospital, Shandong University, Jinan, 250021, Shandong, China. zhouyu19840130@163.com.; Department of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China. zhouyu19840130@163.com.; The Laboratory of Medical Science and Technology Innovation Center (Institute of Translational Medicine), Shandong First Medical University (Shandong Academy of Medical Sciences) of China, Jinan, 250117, Shandong, China. zhouyu19840130@163.com., Wang X; Department of Obstetrics and Gynecology, Shandong Provincial Hospital, Shandong University, Jinan, 250021, Shandong, China. wxt65@sdfmu.edu.cn.; Department of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China. wxt65@sdfmu.edu.cn.; The Laboratory of Medical Science and Technology Innovation Center (Institute of Translational Medicine), Shandong First Medical University (Shandong Academy of Medical Sciences) of China, Jinan, 250117, Shandong, China. wxt65@sdfmu.edu.cn.; Key Laboratory of Birth Regulation and Control Technology of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital, 328 Jingshi East Road, Jinan, 250025, Shandong, China. wxt65@sdfmu.edu.cn., Li L; Department of Obstetrics and Gynecology, Shandong Provincial Hospital, Shandong University, Jinan, 250021, Shandong, China. lilei@sdfmu.edu.cn.; Department of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China. lilei@sdfmu.edu.cn.; The Laboratory of Medical Science and Technology Innovation Center (Institute of Translational Medicine), Shandong First Medical University (Shandong Academy of Medical Sciences) of China, Jinan, 250117, Shandong, China. lilei@sdfmu.edu.cn.
Source: Stem cell reviews and reports [Stem Cell Rev Rep] 2025 Nov; Vol. 21 (8), pp. 2693-2710. Date of Electronic Publication: 2025 Sep 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101752767 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2629-3277 (Electronic) Linking ISSN: 26293277 NLM ISO Abbreviation: Stem Cell Rev Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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