Cardiovascular Effects and Tolerability of GLP-1 Receptor Agonists: A Systematic Review and Meta-Analysis of 99,599 Patients.

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Title: Cardiovascular Effects and Tolerability of GLP-1 Receptor Agonists: A Systematic Review and Meta-Analysis of 99,599 Patients.
Authors: Galli M; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy; Cardiovascular Department, Maria Cecilia Hospital, GVM Care & Research, Cotignola, Italy. Electronic address: mattia.galli@uniroma1.it., Benenati S; Cardiovascular Disease Unit, IRCCS Ospedale Policlinico San Martino, IRCCS Italian Cardiology Network, Genova, Italy., Laudani C; Division of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA., Simeone B; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy., Sarto G; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy., Ortega-Paz L; Division of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA., Rocco E; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy., Bernardi M; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy., Spadafora L; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy., D'Amario D; Department of Translational Medicine, Division of Cardiology, Università del Piemonte Orientale, AOU Maggiore della Carità, Novara, Italy., Greco E; Department of Health and Life Sciences, European University of Rome, Rome, Italy., Frati G; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy; IRCCS NeuroMed, Pozzilli, Italy., Federici M; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy., Mehran R; Center for Interventional Cardiovascular Research & Clinical Trials, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Crea F; Center of Excellence of Cardiovascular Sciences, Ospedale Isola Tiberina - Gemelli Isola, Rome, Italy; Catholic University of the Sacred Heart, Rome, Italy., Angiolillo DJ; Division of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA., Sciarretta S; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy; IRCCS NeuroMed, Pozzilli, Italy.
Source: Journal of the American College of Cardiology [J Am Coll Cardiol] 2025 Nov 18; Vol. 86 (20), pp. 1805-1819. Date of Electronic Publication: 2025 Aug 27.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: Elsevier Biomedical Country of Publication: United States NLM ID: 8301365 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-3597 (Electronic) Linking ISSN: 07351097 NLM ISO Abbreviation: J Am Coll Cardiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1558-3597
DOI:10.1016/j.jacc.2025.08.027